Functional Imaging in Childhood Language Impairment

拟议的研究培训将通过应用课程（秋季，2000年）中获得的知识在两个监督项目（范式发展和范式的应用与SLI儿童）的功能性神经影像学的研究技能，并计划未来的研究应用功能磁共振成像在儿童的特定语言障碍的研究。长期目标是应用结构和功能神经成像来了解语音语言处理和其他基本过程（例如，注意），并确定干预的潜在影响。第一年的拟议研究活动将是开发一个功能磁共振成像线索-目标延迟范式，以检查典型发育中儿童的听觉和视觉方式的定向。第二年将致力于一个指导项目，在该项目中，这种模式将应用于与前一年进行的研究中的典型发育儿童年龄相匹配的SLI儿童。

The proposed research training will develop research skills in functional neuroimaging by applying knowledge obtained during coursework (Fall, 2000) in two supervised projects (paradigm development and application of the paradigm to children with SLI) and to plan for future research applying fMRI to the study of specific language impairment in children. The long-term goal is to apply structural and functional neuroimaging to gain an understanding of the neurobiology underlying speech-language processing and other basic processes (e.g., attention) in children with SLI and to determine the underlying impact of intervention. The proposed research activity for the first year will be to develop an fMRI cue-target delay paradigm to examine orienting in auditory and visual modalities for typically developing children. The second year will be devoted to a mentored project in which this paradigm will be applied to children with SLI who are age-matched to the typically developing children from the study conducted during the previous year.