MINNESOTA STROKE SURVEY

描述(改编自申请人的摘要)：人口模式和 中风的趋势正在发生变化。在多年的稳定和充实之后 中风死亡率的下降，死亡率现在已经持平，甚至可能 在区域和全国范围内都在增加。这种不利的趋势可能与 对高血压或其他因素的检测和控制较差。我们也是 进入包括新的卒中医疗保健的变革期 可能发生变化的治疗方法和新的卫生保健提供制度 中风的结果。 在中风发生动态变化的时候，很少有中心致力于 记录长期趋势并提供数据，为临床医生和公共卫生提供信息 当局对我们国家中风的负担感到担忧。明尼苏达州中风 调查(MSS)过去曾试图提供基于人口的信息， 现在寻求继续并加强这一努力。我们打算调查一下 明尼阿波利斯-t地区30-84岁居民中风住院情况。保罗 都会区(人口245万，1995年估计) 和2001年。具有目标ICD笔划代码的50370随机放电样本将 从调查区域内的每一家医院中挑选，记录将被摘要 由训练有素的护士，中风病例将得到系统的验证和 这是机密。卒中发病率、严重程度、病死率和急性护理 2000-2001年将与以前确定的队列中的类似数据进行比较 住院的中风患者，包括来自 1995年。研究影响卒中后远期预后的因素 现代中风门诊护理的特点，我们建议遵循新的 在最大的健康维护机构之一诊断出中风病例 (HMO)在调查区域。从2001年1月1日到12月31日， 2002年，HMO人群中的新中风病例将在正在进行的 在此基础上进行为期12个月的随访(估计N=850)。面对面采访 患者(或代理人)和照顾者将在2个月和12个月时进行 事件发生几个月后，以确定影响功能变化的因素 中风康复期的生活状况和质量。

DESCRIPTION (Adapted from the Applicant's Abstract): Population patterns and trends for stroke are changing. After many years of steady and substantial decline in stroke mortality, the mortality rates have now leveled and may even be increasing regionally and nationally. This unfavorable trend may be related to poorer detection and control of hypertension or other factors. We are also entering a period of change in the medical care of stroke including new treatment methods and new systems of health care delivery which may change stroke outcomes. At this time of dynamic change in stroke, there are few centers working to document secular trends and provide data to inform clinicians and public health authorities about the burden of stroke in our nation. The Minnesota Stroke Survey (MSS) has sought to provide population-based information in the past and now seeks to continue and enhance that effort. We propose to survey hospitalized stroke among 30-84 year old residents of the Minneapolis-t. Paul metropolitan area (population 2.45 million, 1995 estimate) in the years 2000 and 2001. A 5037O random sample of discharges with target ICD stroke codes will be selected from each hospital in the survey area, records will be abstracted by trained nurses, and stroke cases will be systematically validated and classified. Stroke incidence, severity, case-fatality, and acute care in 2000-2001 will be compared to similar data from previously identified cohorts of hospitalized stroke patients, including a well-characterized cohort from 1995. To study factors influencing long-term outcomes after stroke and to characterize contemporary outpatient care of stroke, we propose to follow newly diagnosed stroke cases in one of the largest Health Maintenance Organizations (HMO) in the survey area. Beginning in January 1, 2001 and through December 31, 2002, new stroke cases in the HMO population will be identified on an ongoing basis and followed for 12 months (estimated N= 850). In-person interviews with the patient (or a proxy) and a care-giver will be conducted at 2 months and 12 months after the event to identify factors that influence changes in functional status and quality of life during recovery from stroke.