Molecular Medicine of Colorectal Cancer

申请人描述 在分子机制的理解上取得了重大进展 结直肠癌（CRC）在过去的十年中。 关键基因的突变， 导致对CRC易感性增加， 化了 这些基因的鉴定使大规模的遗传学研究成为可能。 在人群中筛查受影响的个体。 多种药理 药物也已被证明在预防或治疗 《儿童权利公约》。 这些重大进展可能会影响传统的临床 方法CRC，导致改进的诊断和治疗方法学- 这是一种严重的疾病。 本次会议的目的是聚集 一组来自科学界和临床界的专家调查员 以制定新的方法来诊断和管理CRC。 希望在会议结束时， 研究人员将通过与其他人的互动来发展新的想法， 随后将这些新思想应用到他们的研究领域。

APPLICANT'S DESCRIPTION Significant progress has been made in understanding the molecular mechanisms of colorectal cancer (CRC) in the last decade. Mutations of key genes which lead to increased susceptibility to CRC have been identified and character- ized. The identification of these genes has enabled large-scale genetic screening in the population for affected individuals. Various pharmacological agents have also been shown to be effective in the prevention or treatment of CRC. These major advances are likely to affect the conventional clinical approaches to CRC, leading to improved diagnostic and therapeutic methodolog- ies for this serious disease. The objective of this conference is to assemble a group of expert investigators from both scientific and clinical communities in order to formulate novel approaches to the diagnosis and management of CRC. It is hoped that at the conclusion of the conference each group of investigators will develop new ideas by interacting with the others and subsequently apply these new ideas to their fields of studies.