Emory Epithelial Pathobiology Research Development Center

埃默里上皮病理学研究发展中心成立于2003年6月， 四个新资助的消化系统疾病研究发展中心（DDRDCs）之一，由 NIDDK。该中心的目标是为一群高度专业化和 互动上皮生物学家和病理生物学家在消化系统的意图，提高 研究能力，促进新的研究方向，并促进合作和互动， 调查人员该中心支持的研究主要集中在上皮生物学和 消化道的病理生物学有三个主要主题：炎症/感染，增殖/ 分化和正常生理学。该中心有三个核心：（A）基因表达分析 核心，（B）图像分析核心，和（C）细胞培养核心。在过去的几年里，这些核心已经 在埃默里大学以消化系统疾病为中心的研究项目的发展中发挥了至关重要的作用， 显著提高了中心成员的研究能力， 科学生产力。成立之初，该中心有9名常设调查员（正式成员）和5名 初级调查员（初级成员），合并年度直接费用为2 965 972美元（其中55% 由NIDDK支持）。迄今为止，该中心已发展成为一个由21名正式成员和8名初级成员组成的小组， 成员跨越医学部门（包括消化疾病部门， 内分泌学、肾脏病学、肺与重症监护医学和传染病）、病理学， 埃默里大学医学院生理学、外科学、儿科学和神经学系 埃默里学院的生物学教授此竞争性续期申请的合并年度董事成本 8，862，960美元，其中67.7%由NIDDK资助。因此，在不到4年的时间里，该中心有更多的 其成员增加了一倍多，其基本赠款支持增加了近两倍。自2003年以来，这群 研究人员在同行评审期刊上发表了441篇原创研究文章，其中100篇 包含2名或2名以上的作者是中心成员。此外，至少有124个出版物 工作使用了中心提供的核心服务，其中大多数提到了中心的贡献。 该中心还得到了该机构（联合国人权事务高级专员办事处）的大量财政支助。 院长，医学和病理学讲座，消化疾病科），以实施一项 非常成功的丰富计划，包括试点/可行性项目赠款计划，研究研讨会 系列，年度科学研讨会和咨询委员会会议，以及定期通讯。的 因此，该中心的继续将进一步加强消化系统疾病的研究， 埃默里，重点放在NIDDK支持的特派团内的领域。

The Emory Epithelial Pathobiology Research Development Center was established in June of 2003 as one of four newly funded Digestive Diseases Research Development Centers (DDRDCs) supported by the NIDDK. The goal of the Center is to provide core services to a group of highly specialized and interactive epithelial biologists and pathobiologists in the digestive system with the intention of enhancing research capability, promoting new research directions, and fostering collaboration and interaction among the investigators. Research supported by the Center is mainly focused on epithelial biology and pathobiology of the digestive tract with three overarching themes: Inflammation/Infection, Proliferation/ Differentiation, and Normal Physiology. The Center has three cores: (A) Gene Expression Analysis Core, (B) Image Analysis Core, and (C) Cell Culture Core. In the past few years, these cores have played crucial roles in the development of a digestive diseases-centered research program at Emory and significantly enhanced the research capability of Center members as demonstrated by their outstanding scientific productivity. At its inception, the Center had 9 established investigators (full members) and 5 junior investigators (junior members) with a combined annual direct costs of $2,965,972 (55% of which supported by NIDDK). To date, the Center has evolved into a group of 21 full members and 8 junior members spanning across Departments of Medicine (including Divisions of Digestive Diseases, Endocrinology, Nephrology, Pulmonary & Critical Care Medicine, and Infectious Diseases), Pathology, Physiology, Surgery, Pediatrics, and Neurology in the Emory University School of Medicine, and Department of Biology in the Emory College. The combined annual director costs of this competing renewal application are $8,862,960, 67.7% of which are funded by the NIDDK. Thus, in less than 4 years, the Center has more than doubled its membership and nearly tripled its base grant support. Importantly, since 2003, this group of investigators collectively published 441 original research articles in peer-reviewed journals, out of which 100 contained 2 or more authors that are members of the Center. Moreover, at least 124 of these published work used core services provided by the Center, the majority of which cited the contribution of the Center. The Center has also received substantial amounts of financial support from the institution (Office of the Dean, Chairs of Medicine and Pathology, and Division of Digestive Diseases) with which to implement a highly successful enrichment program including a Pilot/Feasibility Project Grant Program, Research Seminar Series, Annual Scientific Symposium and Advisory Committee Meeting, and periodic Newsletters. The continuation of the Center will therefore further increase the strength of digestive diseases research at Emory with a strong focus on areas within the missions supported by the NIDDK.