RISK FACTORS FOR ATTENTION DEFICIT/HYPERACTIVITY DISORDER

我们正在为这项研究完成第二年也是最后一年的数据收集。数据收集应于2000年7月结束。在这项研究中，我们从父母那里获得了84%的回复率，这对于这种基于社区的研究来说是很高的。在350名参与研究的教师中，约98%的人参与并填写了关于自己、班级和学生的信息。整体来说，我们继续得到校方、教职员和家长对这项研究的大力支持。到目前为止，我们已经完成了对父母的约1000次采访；我们希望最终完成对650例病例和650名对照的采访。我们正在开始对50例使用我们的流行病学病例定义确定的病例进行临床子研究。这些孩子和他们的母亲将接受临床医生的半结构化访谈，我们将收集学校记录、教师评级和心理测试结果。这项子研究的目标是，如果我们的病例是在医生的办公室里看到的，可以接触到关于孩子的所有数据，那么我们的病例中有多大比例可以用另一种障碍来解释。这是一项重要的研究，因为ADHD是一个非常有争议的诊断。我已经将我们的队列文件与州领先测试登记文件联系起来。我们一直在与药品监督管理局合作，以获得有关兴奋剂在北卡罗来纳州各县的分布数据。这将使我们能够确定约翰斯顿县的利率是否是非典型的

We are finishing the second and final year of data collection for the study. Data collection should end in July, 2000. We have achieved an 84% response rate from parents in the study, which is high for this type of community based study. About 98% of the 350 teachers in the study have participated and filled out information about themselves, their class, and their students. Overall, we have continued to have strong support for the study from the School Administration, from teachers and staff, and from parents. So far we have completed about 1000 interviews with parents; we hope to ultimately complete interviews on 650 cases and 650 controls. We are starting a clinical sub-study on 50 cases identified using our epidemiologic case definition. These children and their mothers will be interviewed by a clinician using a semi-structured interview and we will collect school records, teacher ratings, and psychological test results. The goal of the sub-study is to see what proportion of our cases would best be explained by another disorder if they had been seen in a physician's office with access to all the data about the child. This is an important study because ADHD is such a controversial diagnosis. I have linked our cohort files with the State lead testing registry files. We have been working with the Drug Enforcement Administration to obtain data on the distribution of stimulant use across North Carolina Counties. This will enable us to determine whether rates in Johnston County are atypical