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Effects of nevogenesis susceptibility genes and phenotypic correlation with dermoscopic characteristics of nevi

Effects of nevogenesis susceptibility genes and phenotypic correlation with dermoscopic characteristics of nevi
新生易感基因的影响及表型与痣皮肤镜特征的相关性
批准号:
nhmrc : 1004999
负责人:
A/Pr Richard Sturm
金额:
$36.95万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31

项目摘要

项目成果

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中文摘要
翻译
黑色素瘤是一种皮肤癌,由产生色素的细胞引起,在澳大利亚是一个主要的公共卫生问题。我们将研究现有类型的葡萄胎的形态、结构和颜色与其随后发展为黑色素瘤的风险之间的关系。这将是第一项将皮肤镜这一非侵入性检查技术与决定皮肤、头发和眼睛颜色的基因的DNA测试相结合的研究,有助于皮肤癌的早期预测和诊断。
英文摘要
Melanoma is a form of skin cancer that arises from the cells that produce pigment and is a major public health issue in Australia. We will examine the relationship between the form, structure and colour of existing types of moles and their subsequent risk of developing into melanoma. This will be the first study to combine dermoscopy, a non-invasive examination technique, with DNA tests of the genes that determine skin, hair and eye colour, aiding in the early prediction and diagnosis of skin cancer.
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Investigation of the molecular basis of human nevogenesis and melanoma initiation
  • 批准号:
    nhmrc : 1083612
  • 项目类别:
    Project Grants
  • 资助金额:
    $39.89万
  • 财政年份:
    2015
  • 负责人:
    A/Pr Richard Sturm
  • 依托单位:
Human pigmentation genetics, melanocyte biology and skin cancer
  • 批准号:
    nhmrc : 1043187
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $45.79万
  • 财政年份:
    2013
  • 负责人:
    A/Pr Richard Sturm
  • 依托单位:
Ligand interactions of the MC1R receptor and cellular consequences for melanocyte responses to UV-damage
  • 批准号:
    nhmrc : 1023884
  • 项目类别:
    Project Grants
  • 资助金额:
    $38.56万
  • 财政年份:
    2012
  • 负责人:
    A/Pr Richard Sturm
  • 依托单位:
Investigating the role of the NR4A nuclear receptor family in melanocyte function and tumorigenesis
  • 批准号:
    nhmrc : 631510
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $37.03万
  • 财政年份:
    2010
  • 负责人:
    A/Pr Richard Sturm
  • 依托单位:
海外基金