INTEGRATED TRAINING IN REPRODUCTIVE ENDOCRINOLOGY

该计划旨在为两个研究生水平的博士前和四个博士后研究员，每年在生殖生物学提供培训。受训人员将继续从事基础科学或临床部门的学术研究工作。该培训计划已运作了15年，在此期间，74名博士后学员（48名医学博士，8医学博士/哲学博士、18/博士）有22名研究生接受了培训。受训人员由五名成员组成的指导委员会在正式申请生殖内分泌中心后选择，对于博士前学生，则选择生物医学科学研究生课程。研究生将继续攻读博士学位。生物医学科学学位。将为博士提供博士后培训。相关学科的候选人，以及经过临床培训的科学家，本科以上学历，接受过妇产科、儿科或内科专业培训。所有进入研究员将由一个指导小组指导，以确定适当的课程工作，并启动和跟踪研究进展。M.D.没有受过研究生教育的研究员将在3年研究金的第一年参加研究生课程和进行研究。所有学员将参加每周一次的生殖生物学研讨会和研究讲习班，并将参加分子和细胞生殖生物学课程。研究培训将由生殖内分泌中心的16名成员提供，他们在UCSF医学和牙科学院的基础科学和临床部门担任教职。目前的研究计划解决生殖生物学的重要问题，包括：性别决定，生殖道的发育，卵巢和睾丸的生物学，正常和异常生殖功能的内分泌调节和不孕症的遗传学。生殖内分泌中心（REC）实验室和办公室由健康科学教学和研究大楼的两层楼约13，000平方英尺组成。此外，还有一个灵长类动物设施、临床研究单位和转基因屏障设施可供研究。组织学、激素测量、蛋白质分离和测序以及分子生物学核心也可用于培训。

The proposed program is designed to furnish training for two graduate level predoctoral and four postdoctoral fellows per year in reproductive biology. Trainees are expected to go on to academic investigative careers in basic science or clinical departments. The training program has been operative for the past 15 years during which time 74 postdoctoral trainees (48 M.D., 8 M.D./Ph.D.,18/Ph.D.) and 22 graduate students have received training. Trainees are selected by a five member Steering Committee following formal application to the Reproductive Endocrinology Center and, in the case of predoctoral students, to the Biomedical Sciences Graduate Program. Graduate students will pursue a course of study leading to the Ph.D. degree in Biomedical Sciences. Postdoctoral training will be offered to Ph.D. candidates in related disciplines, and also to clinically trained scientists with M.D. degrees and prior specialty training in Obstetrics and Gynecology, Pediatrics or Internal Medicine. All entering fellows will be guided by a mentoring team to determine appropriate course work, and to initiate and follow research progress. M.D. fellows with no prior graduate education will spend the first year of a 3 year fellowship attending graduate level courses and performing research. All trainees will participate in the weekly Reproductive Biology Seminar Program and Research Workshop and will take the Molecular and Cellular Reproductive Biology Course. Research training will be provided by the 16 members of the Reproductive Endocrinology Center who hold faculty positions at UCSF School of Medicine and Dentistry in both basic science and clinical departments. Current research programs address important issues in reproductive biology including: sex determination, development of the reproductive tract, biology of the ovary and testes, endocrine regulation of normal and abnormal reproductive function and genetics of infertility. The Reproductive Endocrinology Center (REC) laboratories and offices consist of approximately 13,000 square feet on two floors of the Health Sciences Instruction and Research Building. In addition a primate facility, clinical research unit and transgenic barrier facility are available for studies. Histology, hormone measurement, protein separation and sequencing, and molecular biology cores also are available for training.