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CORE--Mechanisms of toxicity and cell death

CORE--Mechanisms of toxicity and cell death
核心--毒性和细胞死亡机制
批准号:
6589997
负责人:
TERRENCE J. MONKS
金额:
$7.35万
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-04-01 至 2003-03-31

项目摘要

项目成果

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中文摘要
翻译
描述:这个核心最初被命名为“化学机制” 处置和毒性“,并集中在活性氧物种和 它们在细胞毒性中的作用。然而,四名成员已经离开了核心,而 克莱恩、桑德斯、里奇堡和米勒博士加入了核心,后两位是 德克萨斯大学奥斯汀分校的新预约。最后,沃克博士成了次要的 成员,使成员总数达到10人。核心由以下人员领导 特伦斯·蒙克斯医生。十名成员中有八名位于UT-A。所述的 核心的主题是:(1)细胞和分子的识别 化学物质调节细胞程序性死亡的机制,以及 这些影响与环境引起的疾病之间的关系, 以及(2)化学诱导的胁迫信号通路和细胞的调控 循环递增。
英文摘要
Description: This core was initially named "Mechanisms of Chemical Disposition and Toxicity", and concentrated on reactive oxygen species and their role in cytotoxicity. However, four members have left the core while Drs. Kline, Sanders, Richburg and Miller joined the core, the latter two being new appointments at UT Austin. Finally, Dr. Walker has become a secondary member to bring the total number of members to ten. The core is headed by Dr. Terrence Monks. Eight of the ten members are located at UT-A. The stated themes of the core are: (1) identification of the cellular and molecular mechanisms by which chemicals modulate programmed cell death, and the relationship between these effects and environmental-induced diseases, and (2) chemical-induced modulation of stress signaling pathways and cell cycle progression.
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会议论文
Alleviating Reactive Carbonyl Species-Induced Progenitor Cell Dysfunction in Diabetic Wound Healing
  • 批准号:
    10445242
  • 项目类别:
  • 资助金额:
    $37.48万
  • 财政年份:
    2019
  • 负责人:
    TERRENCE J. MONKS
  • 依托单位:
Alleviating Reactive Carbonyl Species-Induced Progenitor Cell Dysfunction in Diabetic Wound Healing
  • 批准号:
    10221677
  • 项目类别:
  • 资助金额:
    $37.48万
  • 财政年份:
    2019
  • 负责人:
    TERRENCE J. MONKS
  • 依托单位:
Hepatic Metabolism and Susceptibility to Ecstasy Toxicity
  • 批准号:
    8078934
  • 项目类别:
  • 资助金额:
    $32.17万
  • 财政年份:
    2008
  • 负责人:
    TERRENCE J. MONKS
  • 依托单位:
Hepatic Metabolism and Susceptibility to Ecstasy Toxicity
  • 批准号:
    7860382
  • 项目类别:
  • 资助金额:
    $33.16万
  • 财政年份:
    2008
  • 负责人:
    TERRENCE J. MONKS
  • 依托单位:
海外基金