Biofilm-Resistant Dental Unit Water Lines

描述：拟议的研究将调查牙科的修改 一种新型但廉价的单线态光敏剂单元水线 氧气。水中的溶解氧被提升为单线态氧。 低功率可见光。通常进入半透明的光 室内光线的管道应该足够了。单线态氧早已为人所知 作为一种有效的消毒剂。这项第一阶段的研究将验证聚亚安酯 最常用于牙科单位水管的酯类管材可以 用光敏剂进行化学修饰。第二种形式的管材，基于 在聚氯乙烯上，也将使用相同的化学物质生产，以增加 一种有用产品的概率。化学过程的影响和 单线态氧对油管材料的影响及增塑剂的作用 在油管上会对光敏剂进行检查。灯光 将对光敏剂的要求进行调查 横截面和横向。因为如此少量的光是 需要时，半透明管可用于将光分布到 牙科单元的阴影区域。在每个阶段，将对油管进行 被污染的水，并对生物膜的发展进行评估。

DESCRIPTION: The proposed research will investigate the modification of Dental unit water lines with a novel yet inexpensive photosensitizer for singlet oxygen. The dissolved oxygen in the water is promoted to singlet oxygen using low power visible light. The light that normally passes into the translucent tubing from room light should be sufficient. Singlet oxygen has long been known as a potent disinfectant. This Phase I research will verify that polyurethane ester tubing, that which is most commonly used for Dental unit water lines, may be chemically modified with the photosensitizer. A second form of tubing, based on PVC, also will be produced using the same chemistry to increase the probability of a useful product. The effects of the chemical process and singlet oxygen on the tubing material and the effects of the plasticizers used in the tubing on the photosensitizer will be examined. The lighting requirements for the photosensitizer will be investigated both cross-sectionally and laterally. Since such a small amount of light is required, the translucent tubing may be used to distribute the light into shaded regions of the Dental unit. At each stage, tubing will be subjected to contaminated water and evaluated for the development of biofilm.