Statistical/Data Management Center-Pediatric AIDS CTG

描述（由申请人提供）：本申请是一个建议， 作为儿科艾滋病临床统计和数据管理中心， 审判组，隶属于审判组协调和 斯蒂芬·斯佩克特博士提交的运筹学中心申请。我们 总体目标和目的是负责所有统计和数据 管理活动的PACTG，包括：（1）提供统计和 PACTG设计和分析中的流行病学支持和领导 研究;（2）建立和管理中心临床和实验室 数据管理系统;（3）与PACTG研究人员合作， 科学和程序问题以及长期规划，（4）提出和 在研究内和研究间对PACTG数据库进行分析， 与其他组织合作，（5）进行统计 对PACTG使命的核心问题进行研究。 SDMC对PACTG小组主席和儿科执行官负责 以马克思确保我们的职责及时完成 方式和产量高品质的产品，我们有（1）建立统计 和数据管理中心，每个中心都由一个定义明确的管理层进行管理， 行政和组织结构，平行和促进 与PACTG协议团队和委员会的互动;以及（2）组装了一个 高素质和经验丰富的专家在设计， 临床试验和观察性研究的分析。

DESCRIPTION (provided by applicant): This application is a proposal to serve as the Statistical and Data Management Center of the Pediatric AIDS Clinical Trials Group (PACTG), in affiliation with the PACTG Coordinating and Operations Research Center application submitted by Dr. Stephen Spector. Our overall objectives and aims are to be responsible for all statistical and data management activities of the PACTG, including: (1) providing statistical and epidemiological support and leadership in the design and analysis of PACTG studies; (2) establishing and administering a central clinical and laboratory data management system; (3) collaborating with PACTG investigators on scientific and procedural issues and long-range planning, (4) proposing and conducting analyses of the PACTG database both within and across studies and in collaboration with other organizations, and (5) conducting statistical research on issues central to the PACTG's mission. The SDMC is accountable to the PACTG Group Chair and the Pediatric Executive Committee. To ensure that our responsibilities are completed in a timely manner and yield products of high quality, we have (1) established statistical and data management centers, each governed by a well-defined management, administrative and organizational structure that parallels and facilitates interactions with the PACTG protocol teams and committees; and (2) assembled a staff of highly-qualified and experienced specialists in the design, conduct and analysis of clinical trials and observational studies.