CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
批准号:
6476772
负责人:
Fielding Bruder STAPLETON
金额:
$35.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1992
资助国家:
美国
项目状态:
已结题
起止时间:
1992-04-01 至 2004-11-30
中文摘要
该申请寻求一个非常成功的CHRC的更新,
儿科科学家的过渡培训,
儿科的细胞发育方面,
华盛顿大学医学院。这一目标
计划是为了识别,鼓励和支持有前途的年轻人
儿科医生通过促进他们获得的技能,
经验的技能和经验所需的启动独立
调查职业。新的调查员和高级教师顾问
在大学及其附属机构设有实验室,
儿童医院和弗雷德哈钦森癌症研究中心(FHCRC),
在那里,儿科部门已经建立了临床和研究
程序.项目主任负责监督项目的日常运作。
CHRC及其核心实验室。核心实验室提供了一个重点,
加拿大人权委员会新的调查员和某些中央服务(例如,转基因
小鼠)。核心实验室还充分利用了
共享资源和设施服务(例如,转基因小鼠)。核心
实验室还充分利用广泛的共享资源,
每个机构的设施。申请人主要有两大来源
该计划:儿科系内的奖学金计划
积极进行外部招聘。特别强调培养
女性儿科科学家的职业生涯,以及实质性的努力,
正在为该部及其加拿大人权委员会招募少数族裔受训人员。
该计划的支持将是确保充分
保护新儿科研究者获得和巩固
他们成功竞争个人研究所需的技能
来自NIH和类似实体的奖励。
英文摘要
This application seeks renewal of a highly successful CHRC which supports
the transitional training of pediatric scientists studying molecular and
cellular aspects of development in the Department of Pediatrics,
University of Washington School of Medicine. The objectives of this
program are to identify, encourage, and support promising young
pediatricians by facilitating their acquisition of the skills and
experience of the skills and experience required to initiate independent
investigative careers. The new investigators and senior faculty advisors
have laboratories at the University and its affiliated institutions, the
Children's Hospital and Fred Hutchinson Cancer Research Center (FHCRC),
where the Department of Pediatrics has established clinical and research
programs. The Program Director oversees the day-to-day operations of the
CHRC and its core laboratory. The core laboratory provides a focus for the
CHRC new investigators and certain centralized services (e.g., transgenic
mice). The core laboratory also take full advantage of the extensive
shared resources and facilities services (e.g., transgenic mice). The core
laboratory also takes full advantage of the extensive shared resources and
facilities at each institution. There are two major sources of applicants
to the program: fellowship programs within the Department of Pediatrics
and active external recruitments. Particular emphasis is paid to nurturing
the careers of female pediatric scientists, and substantive efforts are
underway to recruit minority trainees to the Department and its CHRC.
Support from this program will be the bridge that assures sufficient
protected time for new pediatric investigators to acquire and consolidate
the skills needed for them to successfully compete for individual research
awards from NIH and similar entities.
期刊论文(27)
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Role of keratinocyte injury in adherence of Streptococcus pyogenes.
角质形成细胞损伤在化脓性链球菌粘附中的作用。
DOI:
10.1128/iai.67.12.6707-6709.1999
发表时间:
1999
期刊:
Infection and immunity
影响因子:
3.1
作者:
[Darmstadt,GL, Mentele,L, Fleckman,P, Rubens,CE]
通讯作者:
Rubens,CE
Analysis of mammalian cis-regulatory DNA elements by homologous recombination.
通过同源重组分析哺乳动物顺式调控 DNA 元件。
DOI:
10.1016/s0076-6879(99)06005-x
发表时间:
1999
期刊:
Methods in enzymology
影响因子:
--
作者:
[Fiering,S, Bender,MA, Groudine,M]
通讯作者:
Groudine,M
Tumor necrosis factor-alpha and interleukin-1alpha decrease the adherence of Streptococcus pyogenes to cultured keratinocytes.
肿瘤坏死因子-α 和白细胞介素-1α 会降低化脓性链球菌对培养的角质形成细胞的粘附。
DOI:
10.1086/315066
发表时间:
1999
期刊:
The Journal of infectious diseases.
影响因子:
--
作者:
[Darmstadt,GL, Fleckman,P, Rubens,CE]
通讯作者:
Rubens,CE
Description and targeted deletion of 5' hypersensitive site 5 and 6 of the mouse beta-globin locus control region.
小鼠 β-珠蛋白基因座控制区 5 超敏感位点 5 和 6 的描述和定向删除。
DOI:
--
发表时间:
1998
期刊:
Blood
影响因子:
20.3
作者:
[Bender,MA, Reik,A, Close,J, Telling,A, Epner,E, Fiering,S, Hardison,R, Groudine,M]
通讯作者:
Groudine,M
Heterogeneous AVPR2 gene mutations in congenital nephrogenic diabetes insipidus.
先天性肾性尿崩症的异质 AVPR2 基因突变。
DOI:
--
发表时间:
1994
期刊:
American journal of human genetics
影响因子:
9.8
作者:
[Wildin,RS, Antush,MJ, Bennett,RL, Schoof,JM, Scott,CR]
通讯作者:
Scott,CR
共 6 条
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:6826278
-
项目类别:
-
资助金额:$21.73万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
Cellular and Molecular Biology of Childhood Disease
-
批准号:7625894
-
项目类别:
-
资助金额:$43.03万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:6736325
-
项目类别:
-
资助金额:$43.13万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:6994417
-
项目类别:
-
资助金额:$42.37万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
Cellular and Molecular Biology of Childhood Disease
-
批准号:8197166
-
项目类别:
-
资助金额:$35.49万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
Cellular and Molecular Biology of Childhood Disease
-
批准号:7762248
-
项目类别:
-
资助金额:$25.26万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:6571744
-
项目类别:
-
资助金额:$43.06万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
Cellular and Molecular Biology of Childhood Disease
-
批准号:7385344
-
项目类别:
-
资助金额:$43.2万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
Cellular and Molecular Biology of Childhood Disease
-
批准号:8005537
-
项目类别:
-
资助金额:$23.0万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:7166801
-
项目类别:
-
资助金额:$7.76万
-
财政年份:2003
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
International Pediatric Nephrology Conference
-
批准号:6314897
-
项目类别:
-
资助金额:$2.3万
-
财政年份:2001
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:2645471
-
项目类别:
-
资助金额:$6.59万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
INSTITUTIONAL SHORT TERM TRAINING FOR MINORITY STUDENTS
-
批准号:2212966
-
项目类别:
-
资助金额:$6.79万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:2025348
-
项目类别:
-
资助金额:$26.35万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:6329905
-
项目类别:
-
资助金额:$35.0万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:2838768
-
项目类别:
-
资助金额:$34.9万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
INSTITUTIONAL SHORT TERM TRAINING FOR MINORITY STUDENTS
-
批准号:2212965
-
项目类别:
-
资助金额:$5.22万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:6125621
-
项目类别:
-
资助金额:$35.0万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT
-
批准号:2201355
-
项目类别:
-
资助金额:$24.67万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
INSTITUTIONAL SHORT TERM TRAINING FOR MINORITY STUDENTS
-
批准号:3545947
-
项目类别:
-
资助金额:$3.13万
-
财政年份:1992
-
负责人:Fielding Bruder STAPLETON
-
依托单位:
海外基金