Training Program in Pediatric Gastroenterology/nutrition

描述（由申请人提供）： 这是一份继续支持加州大学旧金山弗朗西斯科（UCSF）儿科胃肠病学和营养学培训计划的申请。该项目在过去的29年里一直得到资助，是美国西部唯一一个由NIH支持的该专业培训机构。该计划的目标是为学员进行儿科胃肠病学、肝脏病学和营养学的富有成效的研究做好准备。大多数毕业生（70%）已经进入学术生涯。五年前，这项培训补助金进行了重组，以利用加州大学旧金山分校和斯坦福大学合并的优势。随着合并的解散，该计划被重新配置，以认识到当前的学术环境，要求所有学员在医疗保健服务和基于价值的研究的新模式的背景下了解儿科疾病的分子和遗传基础。该计划现在致力于培养学术儿科胃肠病学的高度选择的前景，以在团队框架内发挥作用，协调医学科学家与分子和细胞生物学家，生理学家，生物工程师，人种学家和生物伦理学家的努力。目前的申请提出了一个更系统和简化的方法，（1）在两个主要的职业道路培训-基础研究和临床研究-和（2）减少在任何时候在该计划的受训人数。学员在自己的研究项目中接受2-3年的基础实验室或临床研究方法的强化教学和实践指导。该课程结合了胃肠结构和功能的发展方面的教学与实验室和/或临床研究的实践经验，重点是生长和分化的生物力学，以及干扰有序发展的疾病。教育活动包括正式讲座、由受训人员准备的研讨会、跨学科报告和对正在进行的项目的非正式讨论。受训人员参加生物统计学、计算机科学、生物研究原理和研究伦理学等课程。每个受训者都有一个由经验丰富的导师监督的强制性研究项目。要求是医学博士学位和3年的临床儿科住院医师。具有博士学位和与发育胃肠病学或营养学相关的明确职业目标的申请人也有资格。该计划在儿科胃肠病学，肝病学和营养学部门管理，但利用整个UCSF校园的科学资源。受训者可以在多学科环境中接触导师和实验室，并获得相关的培训资源。培训计划的领导现在集中在梅尔文B博士的直接监督下。海曼，由一个新的K24赠款的指导和临床研究的支持。主要教师包括两名副主任，核心部门教师和高级教师导师在UCSF教授职位。要求每年支助3名受训人员

DESCRIPTION (provided by applicant): This is an application for continued support of the training program in Pediatric Gastroenterology and Nutrition at the University of California, San Francisco (UCSF). The program has been funded continuously for the past 29 years, and represents the only NIH-supported training facility for this specialty in the Western US. The program objective is to prepare trainees for productive research in pediatric gastroenterology, hepatology and nutrition. The majority of graduates (70%) have proceeded to academic careers. Five years ago, this training grant was restructured to take advantage of the merger between UCSF and Stanford University. With dissolution of the merger, the program is reconfigured in recognition of the current academic environment that requires all trainees to understand molecular and genetic bases of pediatric disorders within the context of new modalities of health care services and value-based research. The program now strives to train highly selected prospects for academic pediatric gastroenterology to function within a team framework, coordinating the efforts of medical scientists with molecular and cell biologists, physiologists, bioengineers, ethnographers, and bioethicists. The current application proposes a more systematic and streamlined approach by (1) training within two primary career paths - Basic Research and Clinical Research - and (2) reducing the number of trainees in the program at any one time. Trainees receive 2-3 years of intensive didactic and practical instruction in basic laboratory or clinical research methods in the context of their own research project. The curriculum combines instruction in developmental aspects of gastrointestinal structure and function with practical experience in laboratory- and/or clinically-based research focused on biomechanisms of growth and differentiation, and disorders which interfere with orderly development. Educational exercises include formal lectures, seminars prepared by trainees, interdisciplinary presentations, and informal discussions of ongoing projects. Trainees attend courses in biostatistics, computer science, principles of bioresearch, and investigational ethics. Each trainee pursues an obligatory research project(s) supervised by experienced preceptors. Requirements are a MD degree and 3 years of residency in clinical pediatrics. Applicants with PhD degrees and defined career goals related to developmental gastroenterology or nutrition are also eligible. The program is administered in the Division of Pediatric Gastroenterology, Hepatology and Nutrition, but utilizes the scientific resources of the entire UCSF campus. Trainees have access to preceptors and laboratories, with associated training resources, in a multidisciplinary environment. Training program leadership is now centralized under the direct supervision of Dr. Melvin B. Heyman, supported by a new K24 grant for mentoring and clinical investigation. Key faculty include two Associate Directors, Core Divisional Faculty and Senior Faculty Mentors with professorial positions at UCSF. Support for 3 trainees per year is requested