Physician Scientist Training in Substance Abuse Research

描述：（申请人摘要） 使用修订后的指导临床科学家发展计划奖 （MCSDPA）机制，精神病学系药物滥用司， 耶鲁大学医学院要求我们的5年续约期 医生科学家培训计划，该计划一直提供密集的 药物临床和临床前研究方法培训 虐待我们要求6个职位的教师级医生花3-5年 在耶鲁的药物滥用治疗中心， 在一组兴趣广泛的调查员的指导下进行培训 从分子神经生物学到精神病学。拥有超过30 外部资助的研究项目，我们的研究计划的中心主题 是创新的药理学和行为学的开发和评估， 药物滥用者的治疗。我们的多学科计划使我们能够 从临床前到临床研究， 项目（“实验室”）到临床研究（“床边”）。培训目标是 该计划是为初级教师水平的医生科学家提供一个 有机会投入几乎全职的努力，在初始阶段， 他们的职业生涯学习研究技能和进行研究项目作为一个 开始作为独立临床科学家的职业生涯。初步工作后 在该计划的支持下进行，他们将被引导发展 具有科学价值的研究建议（例如，使用R 03或R 01 这些机制将为研究提供支持， 这个节目的时间。

DESCRIPTION: (Applicant's Abstract) Using the revised Mentored Clinical Scientist Development Program Award (MCSDPA) mechanism, the Substance Abuse Division, Department of Psychiatry at Yale University School of Medicine requests a 5 year renewal period for our Physician Scientist Training Program, which has been providing intensive training in research methods for clinical and preclinical investigation on drug abuse. We request 6 positions for faculty level physicians to spend 3-5 years at Yale's Substance Abuse Treatment Unit obtaining clinical and research training under the mentorship of a team of investigators whose interests range from molecular neurobiology to psychiatric epidemiology. With over 30 externally funded research projects, the central theme of our research program is the development and evaluation of innovative pharmacological and behavioral treatments for substance abusers. Our multidisciplinary program enables us to conduct research that moves rapidly and in both directions from preclinical projects ("bench") to clinical studies ("bedside"). The training goal for this program is to provide physician scientists at the junior faculty level with an opportunity to devote virtually fulltime effort during the initial phase of their careers to learning research skills and conducting research projects as a start to careers as independent clinician scientists. After initial work conducted with the support of this program, they will be guided to develop scientifically meritorious research proposals (using, for example, R03 or R01 mechanisms) which will provide support for research that extends beyond the period of this program.