Gastrointestinal Transit Measurement System

描述（由申请人提供）：胃肠运动障碍是一个重要的健康问题，每年有数百万的医生就诊。在许多患者中，胃肠运输的测量可以提供重要的诊断信息。然而，目前的过境测量技术涉及辐射，无法进行长时间，高度详细的记录，需要充分评估病人。该项目的目标是开发一种新的技术，用于门诊测量胃肠运输的患者运动障碍。这项技术捕捉到胃肠道传输的细节，不涉及辐射，并且能够在患者进行日常生活时长时间记录。在该项目的第一阶段，将构建胃肠运输测量系统（GTMS）的原型并在实验室进行测试。测试将集中在确定胶囊跟踪系统的准确性和系统捕捉瞬态运动的能力。二期将对胃肠功能正常和异常的志愿者进行临床论证试验。

DESCRIPTION (provided by applicant): Gastrointestinal motility disorders are a significant health problem accounting for millions of physician visits each year. In many patients, measurement of gastrointestinal transit can provide important diagnostic information. However, current transit measurement techniques involve radiation and cannot make the long-duration, highly detailed recordings needed to fully evaluate patients. The goal of this project is the development of a new technique for outpatient measurement of gastrointestinal transit in patients with motility disorders. The technique captures the fine details of gastrointestinal transit, does not involve radiation, and is capable of making recordings for extended periods while patients undergo their daily routines. In Phase I of this project, a prototype of the Gastrointestinal Transit Measurement System (GTMS) will be constructed and tested in the laboratory. Testing will concentrate on determining the accuracy of the capsule tracking system and the ability of the system to capture transient movements. In Phase II, clinical demonstration testing will be conducted on volunteer subjects with normal and abnormal gastrointestinal function.