WWW-BASED GENETICS CURRICULUM FOR MEDICAL STUDENTS

描述：(申请人摘要)此R25申请符合PA-96-042。 在接下来的几年里，人类基因组计划将带来新的和 强大的测试、技术和疗法。医学生必须做好准备 这项研究的伦理、法律和社会影响(ELSI)。我们 建议开发、评估和实施基于互联网的教育计划 专门为未来的医生，今天的医科学生写的。我们 建议向医学生传授与遗传学相关的英语学习问题， 尤其是基因检测和咨询。我们将创建一个六人模块 将在互联网上提供的课程供医学生学习 课程总监的要求。每节课将利用一个临床病例。 情景方法，并将包括直接的临床情景，包括 患者和遗传性ELSI问题。每节课都将单独完成。 通过互联网；然而，学生们将能够相互交流 以及通过教育模块与课程总监联系。我们将涵盖以下内容： 1)检测前的知情同意，2)向 S能理解的病人，3)非指导性，4)如何工作 家庭，而不仅仅是个人，5)遗传学如何影响对 与生殖有关的问题，以及6)了解 基因测试。其他重要的ELSI问题将交织在上述问题中 经验教训，包括与遗传信息保密有关的问题， 供应商偏见和利益冲突。如有必要，每节课将包括 分子遗传学、新兴技术和研究的基本讨论 调查结果。一个由精神病学家、遗传学家、 医学教育家和人类学家将整合遗传学的观点 研究人员与执业遗传咨询师和医科学生 来创建内容。我们将评估该模块对人们对 咨询患者、临床实践、自我效能、知识和意识 资源的价值。一项随机研究将使用遗传学对受试者进行比较 使用不包含遗传学的主题的模块向受试者发送模块 信息。临床实践的变化将通过与 接受培训提出与遗传学有关的ELSI问题的模拟患者 和基因测试。在课程的价值已经被科学地 展示了我们将与全美的医学院合作 有兴趣在他们的课程中增加ELSI遗传学模块。如果 培训的成功，将扩大医学生的能力和 为他们在实践中将面临的与遗传学相关的挑战做好准备 医生。

DESCRIPTION: (Applicant's Abstract) This R25 application responds to PA-96-042. Within the next few years, The Human Genome Project will lead to new and powerful tests, technologies and therapies. Medical students must be prepared for the ethical, legal, and social implications (ELSI) of this research. We propose to develop, evaluate, and implement an Internet-based education program specifically written for future physicians, today's medical students. We propose to teach medical students about ELSL issues related to genetics, especially genetic testing and counseling. We will create a module of six lessons that will be available on the Internet for medical students to take at the request of a course director. Each lesson will utilize a clinical-case scenario approach and will include straightforward clinical scenarios involving patients and genetic ELSI issues. Each lesson will be completed individually via the Internet; however students will be able to communicate among themselves as well as with the course director via the educational module. We will cover: 1) informed consent prior to testing, 2) providing genetics information to the patient that s/he can understand, 3) being non-directive, 4) how to work with families rather than just individuals, 5) how genetics can affect discussion of issues related to reproduction, and 6) understanding the repercussions of genetic testing. Other important ELSI issues will be interwoven into the above lessons including issues related to confidentiality of genetic information, provider bias, and conflict of interest. As necessary, each lesson will include basic discussions of molecular genetics, emerging technologies and research findings. A multidisciplinary team composed of a psychiatrist, a geneticist, a medical educator, and an anthropologist will integrate the views of genetics researchers with those of practicing genetic counselors, and medical students to create the content. We will evaluate the module's effect on attitudes toward counseling patients, clinical practice, self-efficacy, knowledge, and awareness of resources. A randomized study will compare subjects using the genetics module to subjects using a module on a topic that does not contain genetics information. Clinical practice changes will be measured using interviews with simulated patients who are trained to bring up ELSI issues related to genetics and genetic testing. After the value of the courses has been scientifically demonstrated we will work with medical schools throughout the United States interested in adding the ELSI genetics module to their curriculum. If successful, the training will expand the capabilities of medical students and prepare them for the genetics-related challenges they will face as practicing physicians.