MULTICHANNEL ARRAY TECHNIQUES: MULTICHANNEL RECORDING & ELECTRODES

将微探针放置在脑深部结构中，如 海马体、斯卡帕神经节、下丘、耳蜗核 深层大脑皮层继续成为人们越来越感兴趣的领域 为我们的外部合作者。Buzsaki博士在 全国会议以及他的出版物引起了极大的轰动 那些在海马区记录的人感兴趣的交易。面临的挑战 使用探头进行这些准备包括握住探头和 插入过程中保持直线轨迹，位置准确 放置在远低于大脑表面的小区域，以及 插入后稳定。我们正在与上市的集团合作 合作研究人员来解决这些问题。探头使用 在插入过程中，长腿往往会弯曲。几名调查人员正在 使用套管准备将探头插入深层结构。 其他人正在探索这种涂层以增强刚性或附着性 更小、更坚固的结构延伸到衬底的背面。新的 插入的方法也在评估它们的能力 增强插页的直线度。自定义探测器已被 由上述调查人员设计，并已被伪造和 由中心提供，安装并连接到所需的连接器。这个 在这个科学子项目中完成的工作使许多人受益 研究人员使用新的定位技术，不仅是在大脑深处 结构，但在其他领域也是如此。

The placement of microprobes into deep brain structures such as hippocampus, Scarpa's ganglion, inferior colliculus, cochlear nucleus and deep cortical layers continues to be a growing area of interest for our external collaborators. Dr. Buzsaki's presentations at national meetings as well as his publications have stirred a great deal of interest from those recording in hippocampus. Challenges in using the probes for these preparations include holding the probe and maintaining a straight trajectory during insertion, accurate site placement in small regions well below the brain surface, and stabilization after insertion. We are working with the listed group of collaborative researchers to solve these problems. Probes with long shanks tend to bend during insertion. Several investigators are using cannular preparations to insert probes into deep structures. Others are exploring the coatings to enhance rigidity, or attachment of small, more rigid structures to the back of the substrate. New methods for insertion are also being evaluated for their ability to enhance the straightness of insertions. Custom probes have been designed by the above investigators and have been fabricated and provided by the Center mounted and bonded to desired connectors. The work done within this scientific sub-project benefits many investigators with new placement techniques, not only in deep brain structures but in other areas as well.