CORE--BIOCHEMISTRY CORE

正在建立生物化学核心，以满足日益增长的需求 蛋白质分离和结构表征的个别项目。 这个核心是从以前的项目2的一部分发展而来的， 黑色素瘤相关抗原的生物化学和差异表达。 作为我们分析少量蛋白质的方法， 从黑色素瘤和黑素细胞系中获得的细胞数量有所改善， 发展到现在大多数所需程序相对 常规，尽管它们仍然高度复杂， 要求很高。 这些资源已经发展到了一个地步， 适当地放在一个核心，而不是一个基础研究项目。 在 此外，多个项目需要这些生化分析， 稳步扩张。

The Biochemistry Core is being established to address a growing need by the individual projects for protein isolation and structural characterization. This core has evolved out of a portion of the previous Project 2, "Biochemistry and Differential Expression of Melanoma-associated Antigens". As our methods for analysis of the small amounts of proteins that are available from melanoma and melanocyte cell lines have improved, they have developed to the point where most required procedures are now relatively routine, although they remain highly sophisticated and technically demanding. These resources have evolved to the point where they are more appropriately placed in a Core as opposed to a basic research project. In addition, the need for these biochemical analyses by multiple projects is steadily expanding.