STRUCTURE DETERMINATION OF RACEMIC D L MONELLIN IN CENTROSYMMETRIC SPACE GROUP

芒果蛋白是最有潜力的甜味化合物之一。 为人所知。我们通过混合等量的DL Monellin产生外消旋 本地(L)Monellin和全D Monellin。的强度统计数据 数据6-3.5E显示中心对称结构的可能性很高。 然而，没有重心限制的2.0E精化表明 D分子与L分子之间可能存在非中心关系 和/或分子周围的水结构。要解决此问题， 这对对起源感兴趣的科学家具有重大意义 生物圈和生命起源的手性，我们需要获得 具有最高分辨率的数据。

The protein monellin is one of the most potently sweet compounds known. We produced the racemic DL monellin by mixing equal amounts of Native (L) monellin and All-D monellin. The intensity statistics of data 6-3.5 E showed high possibility of a centrosymmetric structure. However, 2.0 E refinement without centrommetric constrains suggests that there may be a non-centric relationship between D and L molecules and/or water structure around the molecules. To resolve this issue, which has significant implication to scientists interested in origin of chirality in biosphere and in origin of life, we need to obtain data with highest possible resolution.