XRAY CRYSTALLOGRAPHIC STUDIES OF MURB & MTP PROTEINS

来自大肠杆菌的MurB基因的产物MurB正在被 作为设计的潜在新目标的一个例子进行调查 以及新型抗菌治疗药物的开发。我们需要 同步加速器收集高分辨率原生数据和衍生数据 数据。微粒子甘油三酯转移蛋白(MTP)是 对生物体之间的脂类交换很重要 膜，作为控制胆固醇的目标是有意义的 和甘油三酯水平。我们需要同步加速器来获得原生的 我们需要的数据来解决这个结构。

MurB, the product of the murB gene from Escherichia coli, is being investigated as an example of a potential new target for the design and development of novel antibacterial therapeutics. We need synchrotron to collect high resolution native data and derivative data. The protein Microsomal triglyceride transfer protein (MTP) is important to the exchange of lipid species between biological membranes and is of interest as a target for control of cholesterol and triglyceride levels. We need synchrotron to obtain the native data we need to solve this structure.