DIGITAL HAND ATLAS IN ASSESSMENT OF SKELETAL DEVELOPMENT

描述（改编自摘要）： 骨龄评估是儿科患者经常进行的一项程序 评估他们的成长。 这是诊断中的一个重要步骤， 内分泌疾病的管理，代谢和 生长异常，各种综合征中的成熟减速， 畸形和骨发育不良。 它也用于咨询， 计划整形手术 骨龄评估的一种简单方法是 左手手腕X线片与小参考集的图谱匹配 由Greulich和Pyle在1998年的《自然》中开发的正常标准图谱模式 世纪50年代 然而，这些参考X线片并不反映骨骼 今天的欧洲、非洲、西班牙裔儿童和青少年的发展 或是亚洲血统 因为美国的种族多样性和种族混合 各国正在增加，重新评估使用骨龄标准时， 需要对不同族裔的儿童适用。 这项建议是六年持续努力的第二阶段， 完成一个大型标准集的数字化手绘地图集的开发 四个不同种族的儿童的正常手和手腕图像， 实现一个基于网络的计算机辅助骨龄诊断系统 考核 数字地图集，包括1 120份参考资料 图像和计算机提取的骨骼对象和定量特征， 目前过时的Greulich-Pyle地图集的缺点，并允许 骨龄评估将被计算机化。 这些图像是从 平均分布的正常新生儿至18岁，男性和女性， 欧洲人，非洲人，西班牙人和亚洲人的后裔。 A上的定量特征 在Web服务器上提取患者检查的手部图像，然后进行比较 与图谱数据库中的模式进行比对来评估骨龄。

DESCRIPTION (adapted from the Abstract): Bone age assessment is a procedure frequently performed on pediatric patients to evaluate their growth. It is an important procedure in the diagnosis and management of endocrine disorders, diagnostic evaluation of metabolic and growth abnormalities, deceleration of maturation in a variety of syndromes, malformations, and bone dysplasias. It is also used for consultation in planning orthopedic procedures. A simple method for bone age assessment is atlas matching by a left-hand wrist radiograph against a small reference set of atlas patterns of normal standards developed by Greulich and Pyle in the 1950s. However, these reference radiographs do not reflect skeletal development in children and adolescents of today's European, African, Hispanic or Asian descent. Because racial diversity and racial mixing in the United States are increasing, reevaluation of the use of skeletal age standards when applied to children of diverse ethnicity is needed. This proposal is the second phase of a six-year continuing effort and intends to complete the development of a digital hand atlas with a large standard set of normal hand and wrist images of children of four diverse ethnic groups, and to implement a Web-based computer-aided diagnostic system for bone age assessment. The digital atlas, comprising a large set of 1,120 reference images and computer-extracted bone objects and quantitative features, removes the disadvantages of the currently out-of-date Greulich-Pyle atlas and allows the bone age assessment to be computerized. These images are collected from evenly distributed normal newborn to 18 years of age, male and female, European, African, Hispanic, and Asian descent. Quantitative features on a patient examined hand image are extracted on the Web server and then compared with patterns from the atlas database to assess the bone age.