Ultra-fast Mri For Cardiovascular Applications

心血管应用的超高速磁共振成像在过去的一年里，我们进一步开发了磁共振成像系统实时成像介入过程的能力。我们已经实施了实时公关 能够关闭/打开体积投影，以及实时FISP成像序列调整，以指导基于Gd-DTPA注射后的晚期增强在心肌梗死周围区域进行干预。我们将新的定制重建软件与供应商提供的扫描平面控制软件相结合，以同时查看多个扫描平面。该系统集成了多种扫描参数的实时控制功能，如成像分辨率、投影数量、饱和脉冲、线圈增益和场垫片。扫描室为医生提供两个监视器，扫描台末端有两个键盘控制。一张定制的X光/MR患者床已经被整合到实验室中。我们现在已经开始了一系列的动物实验，演示了左心室注射导管的实时指导。我们已经展示了针头部署和造影剂直接注入心肌的可视化，这些结果将直接影响治疗剂直接进入组织。

ULTRA-FAST MRI FOR CARDIOVASCULAR APPLICATIONS Over the past year we have further developed the ability of MRI systems to image interventional procedures in real-time. We have implemented real-time PR with the ability to toggle off/on a volumetric projection, and real-time FISP imaging sequences tuned to guide interventions in peri-infart zones of the myocardium based on late enhancement after Gd-DTPA injections. We have incorporated new custom reconstruction software with the vendor supplied scan plane control software to view multiple scan planes simultaneously. Real-time control of numerous scanning parameters such as imaging resolution, number of projections, saturation pulses, coil gains, and field shims have been incorporated into the system. Two monitors are available in the scan room for the physician, and two keyboard controls are available at the end of the scanning table. A custom xray/MR patient table has been incorporated into the laboratory. We have now begun a series of animal experiments demonstrating real-time guidance of injection catheters in the left ventricle. We have demonstrated the visualization of needle deployment and injection of contrast agent directly into the myocardium These results will have direct impact on the delivery of therapeutic agents directly into tissues.