Nanostructure surveys of natural and biomimetic dental tissues by 3D SAXS tensor tomography

为了更好地利用现有材料并创造新颖和上级产品，我们需要能够在整个身体的每一个分辨率水平上确定结构。在这项提案中，我们寻求在光束线I22上开发和应用先进的3D SAXS张量断层扫描，以创造一种独特的能力，这将大大扩展我们的表征专业知识，并开辟新的研究途径。该项目的目标是使用酸诱导模型，在牙本质脱矿的不同阶段，使纳米纤维胶原结构演变的重要理解，并了解影响新型生物启发的分层牙科复合材料的机械性能的关键结构因素，旨在仿生设计可靠的牙科修复体和其他类似牙本质的材料。虽然这种仪器将使新的科学跨越一系列看似不同的领域（最初来自牙科材料），但通用方法的发展将团结各种用户，并为研究思想的交叉融合提供一种机制。此外，该项目将作为新的科学开发的基础，导致钻石II和新环的预计低发射率特性。

In our quest to understand the behaviour of natural materials in order to make better use of existing ones and create novel and superior products, we need to be able to determine the structure at every increasing levels of resolution throughout the body. In this proposal, we seek to develop and apply the advanced 3D SAXS tensor tomography at beamline I22 to create a unique capability that will significantly extend our characterisation expertise and open up new avenues of research. The objective of the project is to enable significant understanding of the nanofibrillar collagen structural evolution at different stages of dentine demineralisation using an acid induced model, and the understanding of key structural factors that affect the mechanical performance of novel bio-inspired hierarchical dental composite aiming for biomimetic design of reliable dental prosthesis and other dentine-like materials. Whilst the new science that this instrumentation will enable spans a range of seemingly disparate areas (initially from dental materials), the development of common methodologies will unite the various users and provide a mechanism for the cross-fertilisation of research ideas. Additionally, this project will serve as a basis for new science exploitation leading towards Diamond II and the projected low emittance properties of the new ring.