Protective factors against mental health difficulties in adolescents exposed to adversity, a genetically sensitive approach.

童年逆境与青春期和整个人生过程中的负面心理健康后果有关。然而，一些年轻人似乎对不利经历更有弹性，表现出与没有经历过逆境的同龄人相似的幸福结果。保护性因素的存在是这些差异的一种解释，这被强调为一个需要进一步探索的领域(例如McLaughlin 2016)。我的博士项目旨在进一步了解保护性因素在经历过童年逆境的青少年中针对心理健康问题的作用，并通过使用解释遗传混淆的方法-多基因评分和双胞胎差异设计来检查保护性因素是否对幸福感结果有因果影响。我还试图进一步研究不平等对逆境经历的影响，以社会经济地位衡量，以及在逆境中保护青少年心理健康的因素的作用是否被社会模式所借鉴。

Childhood adversity is associated with negative mental health consequences in adolescence and across the life course. However, some young people appear to be more resilient to adverse experiences, demonstrating wellbeing outcomes which are similar to their peers who have not experienced adversity. The presence of protective factors is one explanation for these variances which has been emphasised as an area requiring further exploration (e.g. McLaughlin 2016).My PhD project seeks to further understanding of the role of protective factors against mental health problems in adolescents who have experienced childhood adversity, and to examine whether protective factors have a causal effect on wellbeing outcomes by using methods which account for genetic confounding - polygenic scores & twin differences designs. I also seek to further examine the influence of inequality on the experience of adversity, measured by socioeconomic position, and whether the role of protective factors for adolescent mental health in the context of adversity is socially patterned.