A Research Center to Reduce Ethnic Disparities in ESRD

说明(申请人提供)：在肾脏健康领域存在很大的种族/民族差异。在美国等待肾脏移植的所有人中，少数族裔占50%以上。然而，由于少数民族捐赠器官的比率反映了他们在人口中的比例，患有终末期肾病的少数民族的肾脏短缺已经达到了危机的程度。这些趋势表明，除了开展能够更好地确定肾移植比率中种族/民族差异的相关性和原因的研究外，还需要进行研究，以确定导致较差健康结果的心理社会和心理神经免疫因素。这些调查结果可用于设计预防运动，并可有效地降低高血压、糖尿病、营养不良和运动不足以及少数群体使用合法和非法药物的流行率。霍华德大学肾脏健康项目输出中心将被构建为一个制度化和永久性的研究中心，将完成研究并测试干预措施和做法，以缩小目前肾脏健康方面的种族/民族差异。该中心将由Clive O.Callender博士领导，他是美国首屈一指的肾脏移植专家，也是创建干预措施以弥补肾脏健康中种族/民族差距的先驱。

DESCRIPTION (provided by applicant): Substantial racial/ethnic disparities exist in the area of renal health. Minority groups are more than 50% of all persons on the waiting list for a kidney transplant in the United States. Yet, because minorities donate organs at a rate that reflects their representation in the population, the shortage of kidneys for minorities with End-Stage Renal Disease has reached crisis proportions. Such trends suggest that in addition to conducting research that can better define the correlates and causes of racial/ethnic disparities in kidney transplantation rates research is also needed to identify psychosocial and psychoneuroimmunological factors that contribute to poorer health outcomes. The findings can be exported to the design of prevention campaigns and that can efficaciously reduce the prevalence of hypertension, diabetes mellitus, poor nutrition and inadequate exercise, and licit and illicit substance use among minorities. The Howard University Project Export Center of Renal Health will be structured to serve as an institutionalized and permanent research center that will complete research and test interventions and practices that can reduce current racial/ethnic differentials in renal health. The Center will be headed by Dr. Clive O. Callender, the nation's premiere kidney transplantation specialist and a pioneer in creating interventions to remedy racial/ethnic gaps in renal health.