Physician Scientist Training in Substance Abuse Research

描述：(申请人摘要) 使用修订后的指导临床科学家发展计划奖 精神病学系物质滥用科(MCSDPA)机制 耶鲁大学医学院要求为我们的 医生科学家培训计划，一直在提供密集的 药物临床和临床前研究方法培训 虐待。我们要求6个教员级别的医生职位，工作3-5年 在耶鲁大学药物滥用治疗小组获得临床和研究 在一组兴趣广泛的调查人员的指导下进行培训 从分子神经生物学到精神流行病学。有30多个人 外部资助的研究项目，我们研究计划的中心主题 是开发和评估创新的药理学和行为学 药物滥用者的治疗。我们的多学科计划使我们能够 开展从临床前到临床前期的快速和双向研究 从项目(“工作台”)到临床研究(“床边”)。这方面的培训目标 该计划是为初级教员级别的内科科学家提供 有机会在项目的初始阶段投入几乎全部的精力 他们的职业生涯是学习研究技能和开展研究项目 开始作为独立临床医生科学家的职业生涯。在初始工作之后 在这个项目的支持下，他们将被引导发展 具有科学价值的研究建议(例如，使用R03或R01 机制)，这将为超越 这一计划的期限。

DESCRIPTION: (Applicant's Abstract) Using the revised Mentored Clinical Scientist Development Program Award (MCSDPA) mechanism, the Substance Abuse Division, Department of Psychiatry at Yale University School of Medicine requests a 5 year renewal period for our Physician Scientist Training Program, which has been providing intensive training in research methods for clinical and preclinical investigation on drug abuse. We request 6 positions for faculty level physicians to spend 3-5 years at Yale's Substance Abuse Treatment Unit obtaining clinical and research training under the mentorship of a team of investigators whose interests range from molecular neurobiology to psychiatric epidemiology. With over 30 externally funded research projects, the central theme of our research program is the development and evaluation of innovative pharmacological and behavioral treatments for substance abusers. Our multidisciplinary program enables us to conduct research that moves rapidly and in both directions from preclinical projects ("bench") to clinical studies ("bedside"). The training goal for this program is to provide physician scientists at the junior faculty level with an opportunity to devote virtually fulltime effort during the initial phase of their careers to learning research skills and conducting research projects as a start to careers as independent clinician scientists. After initial work conducted with the support of this program, they will be guided to develop scientifically meritorious research proposals (using, for example, R03 or R01 mechanisms) which will provide support for research that extends beyond the period of this program.