Molecular Mechanisms in Lymphatic Function & Disease

描述（由申请人提供）：虽然在历史上有些被忽视，但淋巴生物学研究在过去2至5年内经历了急剧的指数增长，这在很大程度上归因于这些研究的增强技术和工具的可用性。淋巴生物学家和研究人员前所未有地需要有一个论坛，围绕这一领域的科学发展进行对话，并确定未来研究工作的方向。最近在生产性淋巴研究中经历了高潮的研究方法包括但不限于：遗传学、生物化学和生物物理学、细胞和分子生物学、生理学和药理学、解剖学、发育生物学和病理学、血管发生和血管生成、肿瘤生物学、肌细胞生物学、间质信号传导机制等。两年一次的戈登研究会议系列淋巴疾病的分子机制已经建立，给这个胚胎领域一个急需的论坛，在一个非常集中的科学家群体中暴露新概念，并促进这些个人之间的合作努力，这对这个领域的持续发展至关重要。 该系列会议将致力于深入探索和讨论与淋巴研究和生物学相关的新兴学科，特别强调淋巴发育，血管生成和治疗性淋巴管生成。将探讨淋巴系统的生理学和人类遗传学，并将重点放在癌症转移的机制及其与淋巴功能和淋巴管生成的关系上。

DESCRIPTION (provided by applicant): While historically somewhat neglected, investigations in lymphatic biology have experienced a dramatic and exponential growth within the last 2 to 5 years, in large part ascribable to the availability of enhanced techniques and tools for these investigations. There is an unprecedented need for lymphatic biologists and investigators to have a forum in which to conduct a dialogue surrounding scientific developments in this field and to determine the direction of future investigative efforts. Investigative approaches that have experienced a recent upsurge in productive lymphatic investigation include, but are not limited to: genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology, vasculogenesis and angiogenesis, tumor biology, muscle cell biology, interstitial signaling mechanisms, and others. A biennial Gordon Research Conference series on Molecular Mechanisms in Lymphatic Disease has been established to give this embryonic field a much-needed forum for the exposure of new concepts among a very focused group of scientists and to foster the collaborative efforts among such individuals that are crucial to the continued advancement of this field. This conference series will be devoted to an in-depth exploration and discussion of the emerging disciplines related to lymphatic research and biology, with special emphasis upon lymphatic development, vasculogenesis and therapeutic lymphangiogenesis. The physiology and human genetics of the lymphatic system will be explored and there will be a focus upon mechanisms of cancer metastasis and its relationship to lymphatic function and lymphangiogenesis.