Gordon Conf: Mammalian Gametogenesis & Embryogenesis

描述（由申请人提供）：了解可存活的卵子和精子产生的分子机制以及胚胎发育的开始对21世纪及以后动物物种的持续生存至关重要。生殖生物学的进展不仅在治疗人类不孕症和低生育能力方面有直接的应用，而且在开发避孕方法方面有改进，在农业工程方面有进展，在野生动物保护方面有新方法。此外，作为多能细胞，配子和早期胚胎为了解核编程和细胞周期调控以及转录、翻译和翻译后控制机制提供了重要的基础研究模型，这些领域在广泛的生物医学应用中具有潜在的意义。戈登哺乳动物配子发生和胚胎发生会议的目的是为交流该领域的最新进展提供一个论坛，并通过提供一个促进互动的轻松环境来促进讨论和辩论。戈登会议设置的一个特别重要的方面是让年轻和成熟的研究人员以及国内和国际科学家共同促进交流，从而在该领域产生新的想法和促进新的合作。本次会议将有三个主要目标：1)展示前沿和发人深省的研究；2)促进临床医生与基础科学家之间的互动；3)培养本领域初级研究人员的职业发展。

DESCRIPTION (provided by applicant): Understanding the molecular mechanisms underlying the production of viable eggs and sperm and the initiation of embryonic development is essential for the continued survival of animal species in the 21st century and beyond. Advances in reproductive biology have immediate application, for not only the treatment of human infertility and subfertility, but also for improvements in developing contraceptive methods, advances in agricultural engineering and novel approaches to wildlife preservation. Moreover, as pluripotent cells, gametes and early embryos provide important models for basic research aimed at understanding nuclear programming as well as cell cycle regulation, and transcriptional, translational, and post-translational control mechanisms, and these areas have potential significance for a wide variety of biomedical applications. The objective of the Gordon Conference on Mammalian Gametogenesis and Embryogenesis is to provide a forum for the exchange of the latest advances in the field, as well as to promote discussion and debate by providing a relaxed setting that fosters interaction. A particularly important aspect of the Gordon Conference setting is the blending of young and established investigators, as well as national and international scientists to promote exchanges that will generate new ideas and foster new collaborations in the field. This conference will address three primary goals: 1) Presentation of cutting edge and thought-provoking research; 2) Fostering interactions between clinicians and basic scientists; and 3) Fostering career development of junior investigators in this field.