Development of Deep Tissue Label-free Microscopy Techniques for Biomedical Applications

该项目旨在开发使用无标记化学成像技术进行组织诊断的深度渗透方法。在这个项目中，远红色波长超过1.5微米将研究其穿透各种组织样品和检索化学成分信息的能力。它将包括建立光学装置，开发方法，样品制备，测量和分析。最初将研究骨样本以诊断骨关节炎和骨质疏松症，但也可能检查其他组织样本。

The project is to develop deep penetration approaches using label-free chemical imaging techniques for tissue diagnosis. In this project far-red wavelengths above 1.5 microns will be studied in their ability to penetrate in various tissue samples and retrieve chemical compositional information. It will involving building an optical setup, developing methodologies, sample preparation, measurements and analysis. Initially bone samples will be studied for osteoarthritis and osteoporosis diagnosis but other tissue samples may be examined.