New Jersey Pediatric AIDS Clinical Trials Consortium

描述(由申请人提供)：针对RFA AI-00-015，新的 泽西州儿童艾滋病联合会(NJ-PAC)将此申请提交给 继续作为儿科艾滋病临床试验单位(PACTU)参加 隶属于协调和运营中心(CORC)，由Dr。 史蒂芬·斯佩克特，推进PACTG的研究议程。新泽西州-PAC 调查人员和资源提供了经验丰富的领导层， 科学贡献和广泛的患者基础 强大的临床基础设施。通过这次合作，新泽西州政治行动委员会？S 产科、儿科和青少年调查员将继续参加 孕妇、婴儿、儿童和青少年进入高度优先的第一阶段， II和III临床试验，这些患者共同登记进入Long 学期结局研究。此应用程序详细说明全面的计划 处理PACTG未来研究议程的所有方面：围产期、初级 治疗、青春期、艾滋病毒并发症和免疫学/免疫学 心理治疗。此外，NJ-PAC及其调查人员也是积极的合作者 与国家和国际团体合作。他的经历和贡献 我们的新泽西州-政治行动委员会调查人员在过去四年的资金周期和 在新泽西州-太平洋地区服务区内有大量不同的艾滋病毒感染者， 将NJ-PAC定位为PACTG未来成功的关键单位 研究议程。

DESCRIPTION (provided by applicant): In response to RFA AI-00-015, the New Jersey Pediatric AIDS Consortium (NJ-PAC) is submitting this application to continue participation as a Pediatric AIDS Clinical Trials Unit (PACTU) affiliated with the Coordinating and Operations Center (CORC), led by Dr. Stephen Spector, to advance the research agenda of the PACTG. NJ-PAC investigators and resources offer a combination of experienced leadership, scientific contributions, and an extensive patient base in the context of a strong clinical infrastructure. Through this collaboration, NJ-PAC?s obstetrical, pediatric, and adolescent investigators will continue to enroll pregnant women, infants, children and adolescents into high priority Phase I, II and III clinical trials, with co-enrollment of these patients into long term outcome studies. This application details comprehensive plans that address all aspects of the future PACTG research agenda: Perinatal, Primary Therapy, Adolescence, Complications of HIV, and Immunology/Immune-Based Therapy. In addition, NJ-PAC and its investigators are active collaborators with national and international groups. The experience and contributions of our NJ-PAC investigators during the last four-year funding cycle and the large, diverse HIV-infected populations within the NJ-PAC service area, position NJ-PAC as a critical unit for the future success of the PACTG research agenda.