Surface functionalisation protocols for optical biosensor technology based on the guided-mode resonance phenomenon

该研究项目将研究基于导模共振现象的光学生物传感器技术的各种表面功能化协议。这项工作的目的是提高这些传感器的性能，解决诸如非特异性结合等问题，并提高该技术对免疫和感染中的一组生物标志物的灵敏度。该项目包括使用约克纳米中心的洁净室和相关设施制造生物传感器，以及在我们的生物化学实验室进行各种功能化协议的实验。

This research project will investigate various surface functionalisation protocols for optical biosensor technology based on the guided-mode resonance phenomenon. The aim of the work is to improve the perfomance of such sensors, to address issues such as non-specific binding and to improve the sensitivity of the technology for a panel of biomarkers in immunity and infection. The project involves making biosensors using the York Nanocentre cleanroom and related facilties as well as experimenting with a variety of functionalisation protocols in our biochemistry laboratory.