Synthesis and Functionalisation of nanomaterials by short pulse laser and its applications
短脉冲激光纳米材料的合成、功能化及其应用
基本信息
- 批准号:RGPIN-2017-04425
- 负责人:
- 金额:$ 2.26万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2022
- 资助国家:加拿大
- 起止时间:2022-01-01 至 2023-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
My research group has made important findings in short-pulsed laser nano material synthesis directly from solid targets (without the employment of chemical agents) and its functionalisation for various applications. We have discovered that synthesized nano-materials possess multiple phases 2) SERS-based ultrasensitive detection: This research program will investigate non-plasmonic SERS & apply the knowledge to develop techniques for in-situ monitoring of cell activity, sensing toxic chemicals, and detecting traces of explosives from standoff distances. 3)All-in-one therapeutic agents: Many of these engineered Bio Nano-Materials are multi-functionalized, such as with SERS enhancement, fluorescent enhancement and biocompatibility. Research of these bio-nanomaterials may lead to new cancer therapeutics that integrates several functions into a single medication that would enable mutli-mode diagnoses and impede the growth of cancer cells with no side effects on healthy cells. Our research in this area will contribute significantly to the improvement of the specificity, selectivity and safety of cancer nanomedicine. 4)Rapid healing wound dressing and antibacterial coating for textiles: The bioactivity and biocompatibility of the engineered 3-D nanostructures will be used for developing new bio-functionalized scaffolds and implantable materials in regenerative medicine and clinical tissue engineering, and the knowledge gained will be used to develop wound dressing and self-cleaning cloth for soldiers. In summary, the proposed research is multidisciplinary in nature and will result in high quality HQP training in the synthesis and functionalisation of next-generation nano-materials for diverse applications in chemical/bio sensing, defence, cancer therapy, wound healing and diagnostic applications.
我的研究小组在直接从固体靶(不使用化学试剂)合成短脉冲激光纳米材料及其用于各种应用的功能化方面取得了重要发现。我们已经发现合成的纳米材料具有多个阶段2)基于SERS的超灵敏检测:该研究计划将研究非等离子Sers并应用知识开发原位监测细胞活性的技术,感测有毒化学品,并从远距离检测爆炸物的痕迹。3)一体化治疗剂:许多这些工程生物纳米材料是多功能的,如Sers增强,荧光增强和生物相容性。对这些生物纳米材料的研究可能会导致新的癌症治疗方法,将多种功能整合到单一药物中,从而实现多模式诊断并阻止癌细胞的生长,而对健康细胞没有副作用。我们在这一领域的研究将大大有助于提高癌症纳米医学的特异性,选择性和安全性。4)用于纺织品的快速愈合伤口敷料和抗菌涂层:工程化3D纳米结构的生物活性和生物相容性将用于开发再生医学和临床组织工程中的新型生物功能化支架和植入式材料,所获得的知识将用于开发士兵的伤口敷料和自清洁布。总之,拟议的研究是多学科的性质,并将导致高质量的HQP培训的合成和功能化的下一代纳米材料在化学/生物传感,国防,癌症治疗,伤口愈合和诊断应用的各种应用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Venkatakrishnan, Krishnan其他文献
SERS Active Nanobiosensor Functionalized by Self-Assembled 3D Nickel Nanonetworks for Glutathione Detection
- DOI:
10.1021/acsami.6b13576 - 发表时间:
2017-02-15 - 期刊:
- 影响因子:9.5
- 作者:
Vijayakumar, Sivaprasad Chinnakkannu;Venkatakrishnan, Krishnan;Tan, Bo - 通讯作者:
Tan, Bo
An atomic-defect enhanced Raman scattering (DERS) quantum probe for molecular level detection - Breaking the SERS barrier
- DOI:
10.1016/j.apmt.2019.04.016 - 发表时间:
2019-09-01 - 期刊:
- 影响因子:8.3
- 作者:
Dharmalingam, Priya;Venkatakrishnan, Krishnan;Tan, Bo - 通讯作者:
Tan, Bo
Early detection and prediction of cancer metastasis - Unravelling metastasis initiating cell as a dynamic marker using self-functionalized nanosensors
- DOI:
10.1016/j.snb.2022.131655 - 发表时间:
2022-03-14 - 期刊:
- 影响因子:8.4
- 作者:
Ganesh, Swarna;Venkatakrishnan, Krishnan;Tan, Bo - 通讯作者:
Tan, Bo
Synthesis of fibrous nanoparticle aggregates by femtosecond laser ablation in air
- DOI:
10.1364/oe.17.001064 - 发表时间:
2009-01-19 - 期刊:
- 影响因子:3.8
- 作者:
Tan, Bo;Venkatakrishnan, Krishnan - 通讯作者:
Venkatakrishnan, Krishnan
Direct laser writing of amorphous silicon on Si-substrate induced by high repetition femtosecond pulses
- DOI:
10.1063/1.3493192 - 发表时间:
2010-10-01 - 期刊:
- 影响因子:3.2
- 作者:
Kiani, Amirkianoosh;Venkatakrishnan, Krishnan;Tan, Bo - 通讯作者:
Tan, Bo
Venkatakrishnan, Krishnan的其他文献
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{{ truncateString('Venkatakrishnan, Krishnan', 18)}}的其他基金
3D quantum biosensor for multiple cancer screening and early diagnosis
用于多种癌症筛查和早期诊断的3D量子生物传感器
- 批准号:
561741-2021 - 财政年份:2021
- 资助金额:
$ 2.26万 - 项目类别:
Idea to Innovation
Portable Raman Analyzer for point-of-care rapid analysis of COVID-19 antibody
用于即时快速分析 COVID-19 抗体的便携式拉曼分析仪
- 批准号:
563655-2021 - 财政年份:2021
- 资助金额:
$ 2.26万 - 项目类别:
Alliance Grants
Ultra-sensitive sensors for the detection of onset metastatic cancers from blood samples
用于从血液样本中检测转移性癌症的超灵敏传感器
- 批准号:
571353-2021 - 财政年份:2021
- 资助金额:
$ 2.26万 - 项目类别:
Alliance Grants
Synthesis and Functionalisation of nanomaterials by short pulse laser and its applications
短脉冲激光纳米材料的合成、功能化及其应用
- 批准号:
RGPIN-2017-04425 - 财政年份:2021
- 资助金额:
$ 2.26万 - 项目类别:
Discovery Grants Program - Individual
COVID-19: Portable Raman Analyzer for point-of-care rapid diagnosis of COVID-19
COVID-19:便携式拉曼分析仪,用于即时诊断 COVID-19
- 批准号:
554386-2020 - 财政年份:2020
- 资助金额:
$ 2.26万 - 项目类别:
Alliance Grants
Synthesis and Functionalisation of nanomaterials by short pulse laser and its applications
短脉冲激光纳米材料的合成、功能化及其应用
- 批准号:
RGPIN-2017-04425 - 财政年份:2020
- 资助金额:
$ 2.26万 - 项目类别:
Discovery Grants Program - Individual
Synthesis and Functionalisation of nanomaterials by short pulse laser and its applications
短脉冲激光纳米材料的合成、功能化及其应用
- 批准号:
RGPIN-2017-04425 - 财政年份:2019
- 资助金额:
$ 2.26万 - 项目类别:
Discovery Grants Program - Individual
Synthesis and Functionalisation of nanomaterials by short pulse laser and its applications
短脉冲激光纳米材料的合成、功能化及其应用
- 批准号:
RGPIN-2017-04425 - 财政年份:2018
- 资助金额:
$ 2.26万 - 项目类别:
Discovery Grants Program - Individual
Synthesis and Functionalisation of nanomaterials by short pulse laser and its applications
短脉冲激光纳米材料的合成、功能化及其应用
- 批准号:
RGPIN-2017-04425 - 财政年份:2017
- 资助金额:
$ 2.26万 - 项目类别:
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超快激光纳米加工及其应用
- 批准号:
341908-2012 - 财政年份:2016
- 资助金额:
$ 2.26万 - 项目类别:
Discovery Grants Program - Individual
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