Mechanisms of Disease in the Newborn Human Infant

描述(申请人提供)：这是一份新的申请 儿科内科院校研究培训助学金 华盛顿大学医学院。长期目标是促进 新生医学和医学领域内科科学家的成长与发展 发育生物学。这项建议的具体目的是利用 该机构的独特资源，包括发育生物学小组 在儿科和发育生物学项目中 生物学和生物医学科学部，建立培训计划 参与的儿科医生和基础科学家的教职人员 共同的兴趣以及频繁的调查和学术互动。这个 该计划旨在为最初两年的实验室提供资金 研究并强调细胞和分子生物学的应用 解决最重要问题中的根本问题的方法 新生婴儿。有足够的空间和资源，学员 将从机构内众多的教育活动中受益， 包括教学课程，以及杂志俱乐部和研讨会 基础科学。项目主管将利用一个执行委员会 还可就方案的运作获得持续的咨询意见 至于选择候选人，确定合适的导师，并进行审查 学术进步。老牌儿科的实质性合作 医生-科学家和基础研究人员在寻求问题 发育生物学提供了一个独特的训练机会 基本实验方法应用中的精选个体 新生儿疾病的治疗和预防。因此，这是 计划应为新的儿科学者提供引领未来的道路 儿童健康这一重要领域的进展。

DESCRIPTION (provided by applicant): This is a new application for an Institutional Research Training Grant within the Department of Pediatrics at Washington University School of Medicine. The long-term objective is to foster the growth and development of physician-scientists in Newborn Medicine and Developmental Biology. The specific aim of this proposal is to utilize the unique resources of the institution, including the Developmental Biology Group in the Department of Pediatrics and the Developmental Biology Program in the Division of Biology and Biomedical Sciences, to establish a training program with a participating faculty of pediatricians and basic scientists who share common interests and frequent investigative and scholarly interactions. The program is intended to provide funding for an initial two years of laboratory investigation and emphasizes the application of cell and molecular biologic approaches to address fundamental issues in the most important problems of newborn infants. Sufficient space and resources are available, and trainees will benefit from the numerous educational activities within the institution, including didactic coursework as well as journal clubs and seminars in the basic sciences. The program directors will utilize an executive committee to obtain continuing advice with respect to the operation of the program as well as to select candidate trainees, identify appropriate mentors, and review scholarly progress. The substantive collaboration of established pediatric physician-scientists and basic investigators pursuing questions in developmental biology provides a unique opportunity for the training of selected individuals in the application of fundamental experimental methods to the treatment and prevention of diseases of the newborn infant. As such, this program should provide for new pediatric scholars to lead the way for future advances in this important area of child health.