GRADUATE TRAINING IN MOLECULAR BIOLOGY AND BIOPHYSICS

描述（由申请人提供）：俄勒冈大学正在进行的分子生物学和生物物理学研究生研究培训项目需要继续支持。这项培训活动以分子生物学研究所为中心，也涉及其他具有相关科学兴趣的研究小组。该研究所是一个研究和研究指导中心，在生物大分子的特性中可以找到对生物现象的理解。目前的研究包括研究病毒、细菌、酵母和高等生物细胞的遗传机制的分子基础；基因表达的控制，包括DNA复制、转录和翻译中的起始、延伸和终止机制；酶的结构和功能；蛋白质与核酸的相互作用；以及发育生物学和分化的某些分子方面。

DESCRIPTION (provided by applicant): Continued support is requested for an ongoing program of graduate research training in molecular biology and biophysics at the University of Oregon. This training activity is centered in the Institute of Molecular Biology, and also involves additional research groups with related scientific interests. The Institute is a center for research and research instruction in areas where understanding of biological phenomena can be found in the properties of biological macromolecules. Current research includes studies of the molecular bases of genetic mechanisms in viruses, bacteria, yeast and cells of higher organisms; control of gene expression, including initiation, elongation and termination mechanisms in DNA replication, transcription and translation; enzyme structure and function; interactions of protein and nucleic acids; and certain molecular aspects of developmental biology and differentiation. During the past three years we have been delighted to recruit six outstanding new junior faculty. These are already having a major impact on our training program and will help to ensure its ongoing success. All molecular biology space is still closely contiguous and interactions between research groups and trainees in different laboratories remain strong. Faculty hold academic appointments in different departments (Biology, Chemistry and Physics), but are housed in adjacent laboratories to maximize interactions and collaboration. Interdisciplinary flexibility is promoted by the opportunity to do research under faculty members from any department.