Graduate Training in Molecular and Cellular Pharmacology

分子和细胞药理学研究生培训

• 批准号: 10175159
• 负责人: Anjon Audhya
• 金额: $ 48.76万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10175159
• 关键词: Molecular; Pharmacology; Training

Program Summary The main objectives of Graduate Training in Molecular and Cellular Pharmacology (GTMCP) at the University of Wisconsin (UW)-Madison are to provide predoctoral-level training in interdisciplinary research at the forefront of quantitative and systems pharmacology and a nucleus around which interdepartmental faculty, students, and scientists from across campus can meet and collaborate. Its overall mission is to provide a highly diverse group of trainees with the skills necessary to enter careers related to the Pharmacological Sciences in academia, industry, government, science education, and public policy. Discovering new approaches to drug delivery and developing novel drugs as therapeutics are cornerstones of the program, with a major emphasis on understanding pathways that are relevant to disease. To accomplish these goals, the curriculum focuses on delivering foundational knowledge in Pharmacology, including mechanisms of drug action, pharmacokinetics, and pharmacodynamics, stressing quantitative thinking and the value of -omic technologies. Carefully evaluated coursework centered on the importance of rigor and reproducibility, responsible conduct of research, safety within the laboratory, and grant writing promote the development of trained PhD scientists who can contribute to the biomedical research workforce. A core group of 29 dedicated faculty trainers has been assembled for this application, representing 10 departments, whose interests focus on understanding molecular, cellular, and physiological mechanisms by which drugs or natural ligands interact with cellular receptors and elicit effects in biological systems. All trainers have robust research programs and were selected based on a demonstrated commitment to mentoring graduate students in Pharmacology. Faculty members work in the interdisciplinary areas of Neuropharmacology, Cancer Pharmacology, Cardiovascular Pharmacology, Endocrine Pharmacology, and Immunopharmacology, and collaborate extensively with one another to create a highly interactive network. Each trainer has received extensive mentor training and understands the importance of strong mentor-mentee relationships in establishing an inclusive and supportive research environment. GTMCP leverages strong institutional support and substantial resources to facilitate the professional development of its trainees. Through its well-funded seminar series, all trainees are provided regular opportunities to develop excellent oral presentation skills and invite outside faculty speakers from top institutions across the country. Research retreats and symposia offer additional opportunities for students to host and interact with prominent members of the Pharmacology community and develop networking skills. GTMCP also boasts considerable trainee diversity, a high retention rate, a rapid time to degree, and an excellent record of trainee publications. Ten slots to support trainees for two years of their early graduate education are requested based on the growing demand for PhD- level scientists trained in Pharmacology and the high quality of students that apply to UW-Madison.

计划摘要 宾夕法尼亚大学分子与细胞药理学研究生培养的主要目标 威斯康星州(威斯康星州)-麦迪逊将在最前沿的跨学科研究方面提供博士前水平的培训 定量和系统药理学和核心，围绕着跨部门的教职员工，学生和 来自校园各地的科学家可以见面并进行合作。它的总体使命是提供一个高度多样化的群体 具有进入学术界药理学相关职业所需技能的受训人员， 工业、政府、科学教育和公共政策。发现药物输送的新方法和 开发新药作为治疗方法是该计划的基石，主要强调 了解与疾病相关的途径。为了实现这些目标，课程重点放在 传授药理学基础知识，包括药物作用机制、药代动力学、 和药效学，强调定量思维和组学技术的价值。仔细评估 课程的核心是严谨和可重复性、负责任的研究方法、安全 在实验室内，资助写作促进了训练有素的博士科学家的发展，他们可以为 生物医学研究队伍。为此，一个由29名专职教员培训人员组成的核心小组已经聚集在一起 应用程序，代表10个部门，其兴趣集中在了解分子、细胞和 药物或天然配体与细胞受体相互作用并诱导作用的生理机制 生物系统。所有培训师都有强大的研究计划，并根据示范的 致力于指导药理学研究生。教职员工从事跨学科的工作。 神经药理学、肿瘤药理学、心血管药理学、内分泌药理学、 和免疫药理学，并相互广泛合作，创建一个高度互动的网络。 每个培训师都接受了广泛的导师培训，并理解强大的导师-受训者的重要性 建立包容性和支持性的研究环境方面的关系。GTMCP利用强大的 机构支持和大量资源，以促进其受训人员的专业发展。穿过 其资金充足的系列研讨会，为所有学员提供定期发展优秀口语的机会。 演讲技巧，并邀请来自全国顶尖学府的外部教师演讲者。研究撤退 和座谈会为学生提供了更多的机会来主持和与 药理学社区和发展网络技能。GTMCP还拥有相当多的实习生多样性， 留存率高，获得学位的时间很快，学员出版物的记录也很好。要支持的10个插槽 基于对博士不断增长的需求，要求学员接受两年的早期研究生教育- 经过药理学培训的高水平科学家和申请威斯康星大学麦迪逊分校的高素质学生。