Noninvasive Home Monitor for Sleep Apnea Testing

描述(申请人提供)：阻塞性睡眠呼吸暂停影响约3-4%的人口，包括儿童。有相当大的相关发病率和死亡率。特别是，它与高血压和心脏病有很强的联系。白天昏昏欲睡会导致交通事故增加，工人产量减少。这种情况的关键诊断测试是通宵睡眠测试或夜间多导睡眠图。尽管这种疾病很严重，但约80%的患者没有得到诊断。这在一定程度上是由于标准多导睡眠图的费用和可用性的缺乏。这导致了人们对便携式测试系统的开发产生了极大的兴趣，这些系统可以在家中为阻塞性睡眠呼吸暂停提供经济、方便和准确的测试。我们提出了一种单一类型的基于传感器的监控系统，该系统将提供一个可靠且简单易用的单元，该单元应该允许经济和高效的家庭测试。虽然我们建议使用单个传感器来实现简单易用的系统，但我们采用了数据分析方法，可以恢复预测阻塞性睡眠呼吸暂停的三个独立指标。这应该允许比目前的便携式系统更准确的测试系统。由于拟议的系统将纠正便携式睡眠测试仪器的主要问题(实用、机械和提供诊断准确性的多种指标)，我们预计该项目将导致成功的商业产品，将有利于大量目前未确诊的美国人。

DESCRIPTION (provided by applicant): Obstructive sleep apnea affects about 3-4% of the population including children. There is considerable associated morbidity and mortality. In particular there is a strong association with hypertension and cardiac disease. Daytime somnolence leads to increased traffic accidents and decreased worker production. The key diagnostic testing for this condition is overnight sleep testing or nocturnal polysomnography. Despite the seriousness of this medical condition about 80 percent of those afflicted are undiagnosed. This is due, in part, to the expense and lack of availability of standard polysomnography. This has lead to a great deal of interest in the development of portable testing systems that provide economical, readily available and accurate testing for obstructive sleep apnea at home. We propose a single type of sensor based monitoring system that would provide a reliable and simple to use unit that should allow for economical and efficient home testing. Although we propose the use of a single sensor to allow for a simple to use system, we incorporate data analysis methods that will allow for the recovery of three independent metrics for prediction of obstructive sleep apnea. This should allow for a more accurate testing system than current portable systems. Since the proposed system will correct the major problems with portable sleep testing instruments (practical, mechanical and provide multiple metrics for diagnostic accuracy), we anticipate that this project would result in a successful commercial product that would be beneficial to a large number of currently undiagnosed Americans.