Molecular Epidemiology of Drug Resistant, Vaccine Preve*

简介（由申请人提供）：我们提议在匹兹堡大学（皮特）公共卫生研究生院建立一个全球传染病研究培训计划。我们计划的主要重点将是流行病学，分子流行病学，以及耐药性，疫苗可预防和食源性传染病的控制。我们项目的使命是为巴西的卫生专业人员提供多学科工具，以便在巴西圣保罗开展这些重要传染病的前沿预防研究。该项目将由流行病学和医学副教授Lee Harrison博士指导，他是美国疾病控制与预防中心资助的马里兰州新发感染项目（EIP）的活性细菌核心监测项目的首席研究员，也是匹兹堡大学公共卫生传染病实验室主任。我们的主要合作机构是Adolfo Lutz研究所，这是圣保罗州立大学的主要参考和研究实验室。匹兹堡大学的众多应用和公共卫生研究活动以及阿道夫卢茨正在进行的研究活动将提供丰富的多学科学术和研究环境。现场正在进行的研究：O157:H7大肠杆菌和其他产生志贺毒素的大肠杆菌、耐抗生素沙门氏菌和肺炎球菌以及脑膜炎球菌感染的流行病学和分子流行病学研究。受训者将在皮特获得大量的培训机会，包括马里兰EIP和各种各样的实验室资源。该方案的一个重点将是流行病学和分子流行病学方面的短期硕士培训，最终目标是为当地提供研究和控制重要新发传染病所需的基础设施。我们还将提供生物信息学和系统发育分析方面的短期培训机会。本应用程序中描述的优秀培训机会提供了极好的研究和培训环境。

DESCRIPTION (provided by applicant): We propose to establish a Global Infectious Disease Research Training Program at the University of Pittsburgh (Pitt) Graduate School of Public Health. The main focus of our program will be in the epidemiology, molecular epidemiology, and control of drug-resistant, vaccine preventable, and foodborne infectious diseases. The mission of our program is to provide Brazilian health professionals with the multidisciplinary tools needed to conduct cutting-edge prevention research in these important infectious diseases in Sao Paulo, Brazil. The program will be directed by Dr. Lee Harrison, Associate Professor of Epidemiology and Medicine, the principal investigator of the CDC-funded Active Bacterial Core Surveillance project of the Maryland Emerging Infections Program (EIP), and the Director of the Public Health Infectious Diseases Laboratory at the University of Pittsburgh. Our main collaborating institution is the Instituto Adolfo Lutz, a premier reference and research laboratory for Sao Paulo State. The numerous applied and public health research activities at the University of Pittsburgh and the ongoing research activities at Adolfo Lutz will provide a rich multidisciplinary academic and research environment. Ongoing research at the sites studies of the epidemiology and molecular epidemiology of Escherichia coli O157:H7 and other shiga-toxin producing E. coli, antimicrobial-resistant Salmonella and pneumococcus, and meningococcal infection. Trainees will have access to substantial training opportunities at Pitt, including the Maryland EIP and a diverse array of laboratory resources. A key focus of the program will be short-term and masters-level training in epidemiology and molecular epidemiology, with the ultimate goal of providing the local infrastructure needed to study and control important emerging infectious diseases. We will also provide short-term training opportunities in bioinformatics and phylogenetic analysis. The excellent training opportunities described in this application provide a superb research and training environment.