University of Pittsburgh Training Program in Antimicrobial Resistance

摘要 抗菌素耐药性是当今世界面临的最紧迫的公共卫生问题之一。然而，a 在这一领域缺乏地方和国家培训机会造成了一个严重的缺口，这可能会影响 我们目前和未来解决抗菌素耐药性的能力。因此，我们建议设立 匹兹堡大学抗菌素耐药性培训计划(PITT TPAR)，该计划将培训两者 抗菌素耐药性高级研究的研究生和博士后研究员。的关键属性 我们令人振奋的新项目包括加州大学无与伦比的资源和机构支持 匹兹堡，以及我们培训教师的多学科专注、承诺、经验和资金。我们的 理念是学员应该接受培训，让他们接触到广泛的高级、尖端的 EDGE，以及在抗菌研究中使用的新方法，以最好地为他们变得有创造力和 独立调查人员。因此，PIT TPAR的总体目标是提供一个协作、 为来自不同学术背景的学员提供跨学科、协调的团队指导工作，以 培养高技能的独立调查人员，他们拥有技术、智力和领导技能，将 使他们能够在抗菌素耐药性领域做出重大贡献。这将通过以下方式实现 共同导师结构，其中一名导师是拟议研究领域的强大内容专家， 另一位(S)将根据研究领域的不同从不同的学科中挑选。的专业知识 我们的导师涵盖了对全面研究抗菌素耐药性至关重要的领域，包括i) 抗药性的发病机制和分子机制，(Ii)微生物基因组学，(Iii)人类微生物组，(Iv) 生物信息学，(V)流行病学和生物统计学，以及(Vi)传染病建模和模拟。我们 设计了独特的教育课程，将提供抗菌素耐药性的核心培训，以及 我们还将培养学员的口头和书面演示技能，并帮助他们建立科学的 这将推动他们的事业发展。总体而言，我们相信PITT TPAR的独特之处在于它将 利用各种细菌、真菌和病毒系统的抗药性概念，目标是 对受训人员进行关于抵抗的基本概念的教育，并使其能够利用共同主题 他们的研究。

SUMMARY Antimicrobial resistance is one of the most pressing public health issues facing the world today. However, a paucity of local and national training opportunities dedicated to this field creates a critical gap that may impact our current and future ability to tackle antimicrobial resistance. Accordingly, we propose to establish the University of Pittsburgh Training Program in Antimicrobial Resistance (Pitt TPAR), which will train both graduate students and post-doctoral fellows in advanced studies of antimicrobial resistance. Key attributes of our exciting new program include the unparalleled resources and institutional support at the University of Pittsburgh, and the multidisciplinary focus, commitment, experience and funding of our training faculty. Our philosophy is that trainees should receive training that exposes them to a broad spectrum of advanced, cutting edge, and novel approaches used in antimicrobial research to best prepare them to become creative and independent investigators. Therefore, the overall objective of the Pitt TPAR is to provide a collaborative, interdisciplinary, and coordinated team-mentoring effort to trainees from diverse academic backgrounds to foster highly-skilled, independent investigators who have the technical, intellectual and leadership skills that will allow them to make major contributions to the antimicrobial resistance field. This will be accomplished through a co-mentorship structure, with one mentor being a strong content expert in the proposed area of research, with the other(s) to be drawn from a range of disciplines as determined by the area of study. The expertise of our mentors covers fields that are crucial for the comprehensive study of antimicrobial resistance, including i) pathogenesis and molecular mechanisms of resistance, (ii) microbial genomics (iii) the human microbiome, (iv) bioinformatics, (v) epidemiology and biostatistics, and (vi) infectious diseases modeling and simulation. We have designed a unique educational curriculum that will provide core training in antimicrobial resistance, and we will also nurture our trainee's oral and written presentation skills, and help them to establish a scientific network that will advance their career. Collectively, we believe that the Pitt TPAR is unique in that it will leverage concepts in drug resistance from diverse bacterial, fungal and viral systems, with the goal of educating trainees in fundamental concepts of resistance, and enable the utilization of common themes for their research.