University of Pittsburgh Training Program in Antimicrobial Resistance

总结 抗生素耐药性是当今世界面临的最紧迫的公共卫生问题之一。但 专门针对这一领域的地方和国家培训机会的缺乏造成了一个严重的差距， 我们当前和未来应对抗菌素耐药性的能力。因此，我们建议设立 匹兹堡大学抗菌素耐药性培训项目（Pitt TPAR），该项目将培训 研究生和博士后研究员在抗生素耐药性的高级研究。的关键属性 我们令人兴奋的新计划包括无与伦比的资源和机构的支持，在大学 匹兹堡，和我们的培训教师的多学科的重点，承诺，经验和资金。我们 理念是，受训者应该接受培训，使他们接触到广泛的先进，切割， 边缘，和新的方法用于抗菌研究，以最好地准备他们成为创造性的， 独立调查员。因此，皮特TPAR的总体目标是提供一个合作， 为来自不同学术背景的学员提供跨学科和协调的团队指导， 培养高技能的独立调查员，他们拥有技术，智力和领导技能， 使他们能够为抗菌素耐药性领域做出重大贡献。这将通过以下方式实现： 共同导师结构，其中一位导师是拟议研究领域的强大内容专家， 其他学生则来自不同的学科，视乎研究范畴而定。的专门知识 我们的导师涵盖了对抗菌素耐药性综合研究至关重要的领域，包括i） 耐药性的发病机理和分子机制，（ii）微生物基因组学，（iii）人类微生物组，（iv） 生物信息学，（v）流行病学和生物统计学，以及（vi）传染病建模和模拟。我们 设计了一个独特的教育课程，将提供抗菌素耐药性的核心培训， 我们还将培养学员的口头和书面表达能力，并帮助他们建立科学的 网络，这将促进他们的职业生涯。总的来说，我们相信皮特TPAR是独一无二的，因为它将 利用来自不同细菌、真菌和病毒系统的耐药性概念， 教育受训者了解抵抗的基本概念，并利用共同的主题， 他们的研究。

SUMMARY Antimicrobial resistance is one of the most pressing public health issues facing the world today. However, a paucity of local and national training opportunities dedicated to this field creates a critical gap that may impact our current and future ability to tackle antimicrobial resistance. Accordingly, we propose to establish the University of Pittsburgh Training Program in Antimicrobial Resistance (Pitt TPAR), which will train both graduate students and post-doctoral fellows in advanced studies of antimicrobial resistance. Key attributes of our exciting new program include the unparalleled resources and institutional support at the University of Pittsburgh, and the multidisciplinary focus, commitment, experience and funding of our training faculty. Our philosophy is that trainees should receive training that exposes them to a broad spectrum of advanced, cutting edge, and novel approaches used in antimicrobial research to best prepare them to become creative and independent investigators. Therefore, the overall objective of the Pitt TPAR is to provide a collaborative, interdisciplinary, and coordinated team-mentoring effort to trainees from diverse academic backgrounds to foster highly-skilled, independent investigators who have the technical, intellectual and leadership skills that will allow them to make major contributions to the antimicrobial resistance field. This will be accomplished through a co-mentorship structure, with one mentor being a strong content expert in the proposed area of research, with the other(s) to be drawn from a range of disciplines as determined by the area of study. The expertise of our mentors covers fields that are crucial for the comprehensive study of antimicrobial resistance, including i) pathogenesis and molecular mechanisms of resistance, (ii) microbial genomics (iii) the human microbiome, (iv) bioinformatics, (v) epidemiology and biostatistics, and (vi) infectious diseases modeling and simulation. We have designed a unique educational curriculum that will provide core training in antimicrobial resistance, and we will also nurture our trainee's oral and written presentation skills, and help them to establish a scientific network that will advance their career. Collectively, we believe that the Pitt TPAR is unique in that it will leverage concepts in drug resistance from diverse bacterial, fungal and viral systems, with the goal of educating trainees in fundamental concepts of resistance, and enable the utilization of common themes for their research.