Reducing social disparities in cancer risk

描述(由申请人提供)：Glorian Sorensen博士，博士，公共卫生硕士，哈佛大学公共卫生学院(HSPH)社会、人类发展和健康教授，Dana-Farber癌症研究所(DFCI)社区研究中心主任。她研究的核心是以工作场所和社区为基础的随机研究，测试针对个人和组织变革的干预措施的有效性。她的研究特别侧重于设计和测试对低收入、多民族人口有效的干预措施。自1986年以来，索伦森博士一直是12项同行评议研究拨款的首席研究员，其中包括8项由NIH资助的R01和1项P01。自1992年以来，她已正式指导了5名博士生、7名博士后研究员和8名初级教职员工。索伦森博士现在准备巩固她的研究项目，并扩大她的指导。她的职业目标是为减少不同社会阶层和种族/民族的癌症风险差异做出重大贡献。为了实现这一目标，她清楚地勾勒出了一套研究和指导目标。对于研究，她的目标是进行严格、精心设计的研究，旨在：(1)确定与癌症风险差异相关的社会背景因素；(2)将了解这些社会背景因素纳入干预设计；(3)测试干预措施的有效性，以减少风险差异；以及(4)开发和测试传播基于证据的干预措施的有效策略。在指导方面，她的目标是为新科学家(包括初级教师、博士后研究员和博士后学生)提供指导，以便他们能够为癌症预防和控制做出重大和有意义的贡献，包括减少癌症风险的差异。此外，她的目标是增加与少数族裔初级调查人员的工作，特别是促进他们参与有色人种社区的癌症预防研究。这个K05将提供索伦森博士50%的努力，其中60%将专注于研究，40%用于指导。DFCI、HSPH和达纳-法伯-哈佛癌症中心为这一应用提供了坚实的机构支持，并将为研究和指导提供受保护的时间。

DESCRIPTION (provided by applicant): Dr. Glorian Sorensen, PhD, MPH, is Professor of Society, Human Development and Health in the Harvard School of Public Health (HSPH) and Director of the Dana-Farber Cancer Institute's (DFCI) Center for Community-Based Research. The core of her research is randomized worksite- and community-based studies that test the effectiveness of interventions targeting individual and organizational change. Her research focuses particularly on designing and testing interventions to be effective for low-income, multiethnic populations. Since 1986, Dr. Sorensen has been the Principal Investigator on 12 peer-reviewed research grants, including eight NIH-funded R01s and one P01. Since 1992, she has formally mentored 5 doctoral students, seven post-doctoral fellows, and eight junior faculty. Dr. Sorensen is now poised to solidify her research program and expand her mentoring. Her career goal is to make significant contributions to reductions in disparities in cancer risk by social class and race/ethnicity. To accomplish this goal, she has clearly delineated a set of research and mentoring objectives. For research, she aims to conduct rigorous, well-designed studies aimed at: (1) identifying social contextual factors associated with disparities in cancer risk; (2) incorporating an understanding these social contextual factors into intervention design; (3) testing the efficacy of interventions to reduce disparities in risk; and (4) developing and testing effective strategies for disseminating evidence-based interventions. For mentoring, she aims to provide mentoring for new scientists (including junior faculty, post-doctoral fellows, and doctoral students), in order that they will be able to make significant and meaningful contributions to cancer prevention and control, including to the reduction in disparities in cancer risk. In addition, she aims to increase her work with minority junior investigators, with the particular aim of promoting their participation in cancer prevention research for communities of color. This K05 will provide for 50% of Dr. Sorensen's effort, 60% of which will be focused on research and 40% on mentoring. The DFCI, HSPH, and Dana-Farber- Harvard Cancer Center have provided solid institutional support for this application, and will provide protected time for research and mentoring.