EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION

描述(由申请人提供)： 威斯康星州国家灵长类研究中心(NPRC)计划将一个专门的研究设施(SRF)包括在医学院的跨学科研究综合体(IRC)中。我们NPRC的SRF将允许急需的非人类灵长类研究空间的扩展，特别是服务于快速增长的干细胞移植领域。此外，将SRF设在IRC内，使华盛顿大学医院和诊所、韦斯曼中心的移植外科医生和干细胞科学家以及医学院和凯克生物成像实验室的成像设施近在咫尺。完成IRC中的SRF可以有效地利用这笔C06资金，因为IRC外壳将与其他支持一起构建，并且通过将非人类灵长类(NHP)研究IRC置于NPRC的控制之下，提供了行政和管理效率。 具体地说，此处请求的支持将实现： 建造6个房间，最多容纳168只成年猕猴，以及邻近的3个治疗室，供这些动物使用(见图8) 建造笼架清洗设施(见图13附录2) 建造四个专业测试室(见图8附录2) 采购设备：灵长类笼子和笼子垫圈 该项目(6,061个ASF)的完成将使PHS支持的研究--使用NHP，特别是在干细胞生物学和再生医学领域--能够更有效地扩大和更接近医学院的医生和科学家。

DESCRIPTION (provided by applicant): The Wisconsin National Primate Research Center (NPRC) is planning a Specialized Research Facility (SRF) to be included in the Medical School's Interdisciplinary Research Complex (IRC). Our NPRC's SRF will allow for much-needed expansion of non-human primate research space, particularly to serve the rapidly growing area of stem cell transplantation. Furthermore, siting the SRF within the IRC provides critical proximity to transplant surgeons and stem cell scientists at the UW Hospital and Clinics and at the Waisman Center, as well as to imaging facilities at the Medical School and Keck Biological Imaging Laboratory. Finishing out the SRF in the IRC makes efficient use of this C06 funding, because IRC shell will be built with other support, and it provides administrative and managerial efficiency by bringing non-human primate (NHP) research IRC under control of the NPRC. Specifically, the support requested herein will enable:  Construction of 6 rooms for housing up to 168 adult macaques and 3 adjacent treatment rooms for use of these animals (see Fig. 8)  Construction of a cage rack washing facility (see Appendix 2, Fig. 13)  Construction of four specialty-testing rooms (see Appendix 2, Fig. 8)  Purchase of equipment: primate caging and cage washer Completion of this project (6,061 ASF) will enable efficient expansion and greater proximity of PHS supported research-using NHP, particularly in areas of stem cell biology and regenerative medicine, to physicians and scientists at the Medical School.