Understanding Consent to Tissue Donation

描述：(改编自应用程序)尽管组织 捐赠具有更大的公共健康影响，并可能影响许多 捐赠者家庭和接受者比实体器官捐赠更多，几乎没有研究 已经完成了同意程序。捐献的组织提供心脏瓣膜 癌症截骨术的置换、植皮和置换 病人。它们被用于假肢手术，面部消瘦的治疗， 以及许多其他程序。据估计，数以万计的患者 都有资格捐赠组织。尽管如此，大多数对纸巾的要求 捐赠被拒绝(同意率不高于35%)。多数 重要的是，最近的争议引发了人们对请求如何 为捐献组织而制造的。这项为期4年的研究将直接检查组织 组织库工作人员使用的请求流程。我们将评估以下决定因素 家人？捐赠组织的意愿，他们的信息需求，以及 同意做法是否充分。1400个符合组织条件的家庭样本 决策者及其组织员工需求者将在30多个月内招聘- 一个月的期间。病例将从13个国家样本中随机抽取 决定捐献家庭成员的家庭组织库？S 组织。这项研究将从三个来源收集数据：1)符合捐赠者资格 病人？家庭；2)直接参与征求同意的请求者 组织捐献；3)组织捐献请求的录音。 这项研究将是第一次全面检查组织同意书 捐款。

DESCRIPTION: (Adapted from the Application) Despite the fact that tissue donation has greater public health implication and potentially affects many more donor families and recipients than solid organ donation, little research has been done on the consent process. Donated tissues provide heart valve replacements, skin grafts, and replacement of amputated bone in cancer patients. They are used in prosthetic surgery, treatment of facial wasting, and many other procedures. It is estimated that tens of thousands of patients are eligible to donate tissues. Nonetheless, most requests for tissue donation are refused (consent rates are no higher than 35%). Most importantly, recent controversies have raised questions about how requests are made for tissue donations. This 4-year study will directly examine the tissue request process used by Tissue Bank staff. We will assess the determinants of families? willingness to donate tissues, their informational needs, and the adequacy of consent practices. A sample of 1,400 tissue-eligible family decision makers and their tissue staff requesters will be recruited over a 30- month period. Cases will be randomly selected from a national sample from 13 tissue banks of families who made decisions about donating a family member?s tissue. This study will collect data from three sources: 1)donor-eligible patients? families; 2) requesters directly involved in asking for consent to tissue donation; 3) audiotaped recordings of the request for tissue donation. This study will be the first to comprehensively examine consent to tissue donation.