LSU DENTAL COBRE: STATISTICAL CORE

统计核心的总体任务是为科布雷的项目提供研究设计、样本量估计/统计能力分析、统计方法和数据库管理等领域的支助。通过统计核心发展和实施服务是该中心取得全面成功的关键。统计核心不仅在提供统计服务方面发挥关键作用，而且在促进初级首席调查员了解研究设计和数据分析的重要性方面也发挥了重要作用。统计核心将为Cobre PIs和中心成员提供：1.关于研究设计、样本量估计、统计分析计划和研究建议的咨询。2.数据库管理系统和质量控制程序的开发和管理。3.研究数据的统计分析、结果的陈述和解释。4.教育服务，支持研究人员在研究设计和分析方面的发展。5.加强统计核心服务，为科布雷带来最先进的能力。统计核心将支持所有COBRE项目的研究工作。安全的基于网络的数据输入界面将允许使用SAS IntrNet(R)软件从笔记本电脑输入椅子端的数据。该核心将与调查人员密切合作，确保及时、准确和高效地收集和分析研究数据。除了管理研究数据的收集和存储外，核心还将负责数据分析、解释和提出研究结果。该核心还将协助数据监测委员会编写报告、摘要和分析，供会议和中期分析审查。

The overall mission of the Statistical Core is to provide support in the areas of study design, sample size estimation/statistical power analysis, statistical methodology and database management for the projects in the COBRE. The development and implementation of services through the Statistical Core is key to the overall success of the Center. The Statistical Core has a crucial role in not only providing statistical services but in contributing to the mentoring process for the junior Principal Investigators (JPIs) in developing their understanding of the importance of study design and data analysis. The Statistical Core will provide the COBRE PIs and members of the Center with: 1. Consultation on study design, sample size estimation, statistical analysis plan, and research proposal. 2. Development and management of database management system and quality control procedures. 3. Statistical analysis of study data, presentation and interpretation of results. 4. Educational services to support investigator development in study design and analysis. 5. Enhancement of statistical core services to bring state of the art capabilities to the COBRE. The Statistical Core will support research efforts for all COBRE projects. Secure web-based data entry interfaces will allow chair-side data entry from a laptop computer using SAS IntrNet (R) software. The core will work closely with investigators to ensure timely, accurate, and efficient collection and analysis of study data. In addition to managing the collection and storage of study data, the core will be responsible for data analysis, interpretation and presentation of study results. The core will also assist the data monitoring committees by preparing reports, summaries and analyses for review at meetings and interim analyses.