REBASE--THE RESTRICTION ENZYME DATABASE

这个项目是关于维持和分发一个关于限制性内切酶及其相关甲基化酶的连贯和全面的信息数据库。REBASE自1975年以来一直存在，目前在SYBASE下以关系格式实现。信息从已发表的文献和研究者在发表前或发表后直接提交的文献中进入数据库。大约11%的条目不是通过REBASE发布的。这些信息通过科学文献的正式出版物和各种电子格式在全世界传播。因此，每月发布更新，并通过自动电子邮件列表将选定的文件分发给350多个站点。此外，这些信息可通过匿名FTP或通过万维网获得。在每月维护和更新的文件中，有许多更广泛使用的计算机程序使用的专业文件，如GCG， MacVector， DNA Strider等。这些文件可以随时使用，并包含有关所有特性及其商业可用性的最新信息。通过REBASE提供的信息是所有研究人员计划裂解和/或宗教DNA实验的关键。它是生物技术实践的独特资源，其内容被研究卫生保健社区的许多部门直接或间接使用。

This project is concerned with the maintenance and distribution of a cohesive and comprehensive database of information about restriction endonucleases and their associated methylases. REBASE has been in existence since 1975 and is currently implemented in a relational format under SYBASE. Information enters the database both from the published literature and by direct submission from the investigators either prior to publication or instead of publication. Approximately 11% of the entries are unpublished other than through REBASE. The information is disseminated throughout the world both by formal publication in the scientific literature and in a variety of electronic formats. Thus, monthly updates are posted and selected files distributed through an automatic email list to more than 350 sites. In addition, the information is available by anonymous FTP or through the World Wide Web. Among the files maintained and updated monthly are specialized ones that are used by many of the more widely used computer programs, such as GCG, MacVector, DNA Strider etc. These files are ready to use and include up-to-date information about the full range of specificities and their commercial availability. The information available through REBASE is key to all investigators planning experiments to cleave and/or religate DNA. It is a unique resource for the practice of Biotechnology and its contents are used directly or indirectly by many sections of the research health care community.