REBASE--THE RESTRICTION ENZYME DATABASE

该项目涉及一个维护和分配 关于限制的连贯和全面的信息数据库 核酸内切酶及其相关的甲基化酶。 REBASE已经在 自1975年以来一直存在，目前以关系格式实现 根据《 信息进入数据库， 文献或研究者直接提交， 出版或不出版。 约三分之二的 除了通过REBASE之外，目前的条目未发布。 的信息 通过正式出版物在全世界传播， 科学文献和各种电子格式。 因此，每月 通过自动电子邮件发布更新和分发选定的文件， 邮件列表到大约125个站点。 此外，有关资料可由 匿名FTP或通过WAIS。 其他分发机制包括 建议包括通过万维网。 在每月维护和更新的档案中，有一些专门的档案， 被一些更广泛使用的计算机程序所使用，例如GCG和 智能遗传学。 这些文件随时可以使用，并包括最新的 关于全部特性及其商业用途的信息 空房的 通过REBASE获得的信息是所有 研究人员计划进行切割和/或重新连接DNA的实验。 这是一个 生物技术实践的独特资源及其内容被使用 直接或间接由研究医疗保健的许多部门 社区

This project is concerned with the maintenance and distribution of a cohesive and comprehensive database of information about restriction endonucleases and their associated methylases. REBASE has been in existence since 1975 and is currently implemented in a relational format under Sybase. Information enters the database both from the published literature or by direct submission from the investigators either prior to publication or instead of publication. Approximately two thirds of the present entries are unpublished other than through REBASE. The information is disseminated throughout the world both by formal publication in the scientific literature and in a variety of electronic formats. Thus monthly updates are posted and selected files distributed through an automatic E- mail list to about 125 sites. In addition, the information is available by anonymous FTP or through WAIS. Additional distribution mechanisms are proposed including through World Wide Web. Among the files maintained and updated monthly are specialized ones that are used by some of the more widely used computer programs, such as GCG and Intelligenetics. These files are ready to use and include up to date information about the full range of specificities and their commercial availability. The information available through REBASE is key to all investigators planning experiments to cleave and/or religate DNA. It is a unique resource for the practice of Biotechnology and its contents are used directly or indirectly by many sections of the Research Health Care Community.