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Kinetics of Protein Absorption on Lipid Bilayers; Atomic

Kinetics of Protein Absorption on Lipid Bilayers; Atomic
脂质双层上蛋白质吸收的动力学;
批准号:
7013047
负责人:
EMILIOS K DIMITRIADIS
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
了解驱动和组织蛋白质在生物膜上吸附的机制是阐明膜介导的蛋白质功能的基础。理想化的蛋白质在表面吸附的理论动力学研究指出,有趣的现象依赖于蛋白质的形状和电荷,但也强烈依赖于吸附表面的组织。原子力显微镜(AFM)提供了成像实际吸附过程的可能性。为此,我们正在使用原子力显微镜,并将结果与理论模型预期的结果进行比较。
英文摘要
Understanding the mechanisms that drive and organize protein adsorption onto biological membranes is fundamental to clarifying membrane-mediated protein function. Idealized, theoretical kinetic studies of protein adsorption onto surfaces point to interesting phenomena that depend on shape and charge of the proteins, but also strongly on the organization of the adsorbing surface. The atomic force microscope (AFM) offers the possibility of imaging the actual adsorption process. We are using the AFM to that end and to compare the results with those anticipated by the theoretical models.
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Elastic Properties Of The Tectorial Membrane
PROBING ELASTICITY WITH THE ATOMIC FORCE MICROSCOPE
Magnetic Resonance Elastography
Probing The Elasticity Of Biological Samples With The At
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