Construction - Chronic Disease Clinical Research Center

描述（由申请人提供）：拟议的研究建设项目的目标是在洛杉矶生物医学研究所（LA BioMed）提供一个最佳的环境，在其中进行慢性疾病的协作，跨学科，转化研究。我们建议建设一个2层，23171平方英尺（2153平方米）的慢性疾病临床研究中心（CDCRC），该中心将巩固多个研究慢性疾病的研究小组的合作研究项目，包括动脉粥样硬化，慢性阻塞性肺疾病（COPD）和艾滋病毒。洛杉矶生物医学中心成立于1953年，是一家独立的非营利性研究机构，每年获得6000万至7000万美元的资助。位于港口-加州大学洛杉矶分校医疗中心（HUMC） 72英亩的土地上，大多数洛杉矶生物医学研究项目都被安置在有66年历史的破旧木制营房里。这些老化结构分散且无法修复，不利于科学合作、扩大研究活动或为研究参与者提供适合的环境。继续使用这些营房使得难以吸引和留住成功的调查人员。在过去的20年里，已经建造了四座新的研究大楼，但这些现代化设施的空间有限。尽管超过60%的洛杉矶生物医学中心拨款支持临床研究，但现代临床研究领域严重短缺。拟议的CDCRC将位于洛杉矶生物医学研究园区内，并将包括调查员和研究人员的空间；门诊研究门诊，设有专用病人停车场；研究药房;标本处理实验室和储存；心脏CT（计算机断层扫描）阅读中心；运动生理学、肺功能和心脏实验室；研究记录存储；还有一间会议室，用于进行病人和员工培训。该建议包括支持该设施所需的固定设备项目，包括两个生物安全柜和壁挂式检查室诊断设备。非固定设备要么目前可用，要么将由洛杉矶生物医学中心采购。CDCRC将允许研究慢性疾病的研究人员扩大他们的临床研究活动，为服务不足的少数民族社区提供有希望的新疗法和疗法，并为当地和全国的转化研究议程做出贡献。新设施将刺激洛杉矶生物医学中心的研究环境，允许联邦资助的研究人员过渡到现代化的研究大楼，作为招聘新研究人员和学员的重点，并在建设期间及以后创造就业机会。LA BioMed完全致力于确保该建筑按照NIH的规范，在规定的时间内建造，并采用绿色，可持续技术的最高标准。

DESCRIPTION (provided by applicant): The goal of the proposed research construction project is to provide an optimal environment at Los Angeles Biomedical Research Institute (LA BioMed) in which to conduct collaborative, interdiscliplinary, translational research in chronic diseases. We propose the construction of a 2-story, 23,171 sq ft building (2,153 m2) Chronic Disease Clinical Research Center (CDCRC) which will consolidate the collaborative research programs of multiple investigator groups who are studying chronic diseases, including atherosclerosis, chronic obstructive pulmonary disease (COPD) and HIV. LA BioMed, founded in 1953, is an independent, non-profit research institute with $60-$70 million in annual grant funding. Located on the 72-acre grounds of Harbor-UCLA Medical Center (HUMC), the majority of the LA BioMed research programs are housed in 66-year old deteriorating wooden barracks. These aging structures are scattered and beyond repair, and are not conducive to scientific collaboration, expansion of research activities or providing an environment suited for research participants. The continued use of these barracks makes it difficult to attract and retain successful investigators. Over the past 20 years, four new research buildings have been constructed but space in these modern facilities is limited. Although more than 60% of LA BioMed grant funding supports clinical research, there is a severe shortage of modern, clinical research areas. The proposed CDCRC will be located within the LA BioMed Research Park and will include space for investigators and research personnel; outpatient research clinic with dedicated patient parking; research pharmacy; specimen processing laboratory and storage; cardiac CT (computerized tomography) reading center; exercise physiology, pulmonary function and cardiac laboratories; research records storage; and a meeting room to conduct patient and staff training sessions. Included with this proposal are fixed equipment items that are needed to support the facility, including two biosafety cabinets and wall-mounted exam room diagnostic sets. Non-fixed equipment is either currently available or will be procured by LA BioMed. The CDCRC will allow investigators who study chronic diseases to expand their clinical research activities, provide promising new treatments and therapies to an underserved ethnic minority community, and contribute to the translational research agenda locally and nationally. The new facility will stimulate the research environment at LA BioMed, allow for the transition of federally-funded investigators into modern research buildings, serve as a focus for recruitment of new researchers and trainees, and lead to jobs creation during the construction period and beyond. LA BioMed is fully committed to ensuring that the building is constructed according to NIH specifications, within the prescribed timeline and with the highest standards for green, sustainable technology.