Einstein Stem Cell Research Institute

描述（由申请人提供）：阿尔伯特·爱因斯坦医学院战略研究计划建立了一个干细胞研究所（SCRI），将在干细胞研究和再生医学方面创造交叉机会。目前，爱因斯坦有一个由21名参与干细胞研究的研究人员组成的教师基地，他们分布在校园的各个建筑物中。鉴于其在爱因斯坦的战略计划中的关键作用，SCRI已承诺在新的2亿美元的遗传和转化医学价格中心的一个完整的翅膀，加上教师招聘和核心设施的发展资源。价格中心容纳了研究所的新主任，以及发挥重要作用的表观基因组学中心。该提案旨在为12名高级干细胞研究人员创造空间，通过翻新和现代化实验室为干细胞研究设施的综合网络创造扩大的空间。SCRI由外部来源支持，包括NIH和纽约州干细胞研究计划。我们建议围绕四个研究领域组织SCRI：1）干细胞生物学，2）干细胞遗传学，3）癌症干细胞和4）转化干细胞研究。为了与现有的干细胞研究人员协同，我们设想SCRI将通过在细胞生物学，遗传学，发育和分子生物学部门共同招聘教师来扩大基础和转化干细胞研究。根据战略计划，这三个部门共提供了17，970 nsf的实验室空间，用于容纳新的干细胞研究人员，以扩大科学研究基础。因此，这项申请的重点是扩大新的干细胞研究所，以创建新的实验室，并扩大相关的干细胞核心设施，用于细胞分选和细胞移植。C06基金将创造85个与建筑相关的工作岗位和68个新的研究实验室工作岗位。这对布朗克斯的140万人来说，既是经济上的关键，也是创造科学创新的主要驱动力，以创造多种疾病的治疗方法。布朗克斯是纽约内失业率最高的县之一。

DESCRIPTION (provided by applicant): The Albert Einstein College of Medicine Strategic Research Plan established a Stem Cell Research Institute (SCRI) that will create cross-cutting opportunities in stem cell research and regenerative medicine. Currently, Einstein has a faculty base of 21 investigators involved in stem cell research who are located in various buildings across the campus. Given its key role in Einstein's Strategic Plan, the SCRI has been committed a full wing in the new $200 million Price Center for Genetic and Translational Medicine, plus resources for faculty recruitment and development of core facilities. The Price Center houses the new director of the Institute, as well as the Center for Epigenomics that plays a major role. This proposal aims to create space for 12 senior stem cell investigators, generating the expanded space by renovating and modernizing laboratories for an integrated network of stem cell research facilities. The SCRI is supported by external sources, including the NIH and the New York State Stem Cell Research program. We propose to organize the SCRI around four areas of research: 1) Stem Cell Biology, 2) Stem Cell Genetics, 3) Cancer Stem Cells, and 4) Translational Stem Cell Research. In order to synergize with existing stem cell researchers, we envision that the SCRI will expand basic and translational stem cell research by co-recruitment of faculty in the departments of Cell Biology, Genetics, and Developmental and Molecular Biology. Pursuant to the Strategic Plan, these 3 departments have contributed a total of 17,970 nsf of laboratory space to house new stem cell investigators to expand the scientific research base. The focus of this application is therefore to expand the new Stem Cell Research Institute to create new laboratories and to expand the related stem cell core facilities for cell sorting and cell transplantation. The C06 funds will create 85 jobs related to construction and 68 new research laboratory jobs. This is both economically critical for the 1.4 million people in the Bronx, the county within New York that has one of the highest unemployment rates, as well as creating a major driver of scientific innovation to create the cures for multiple diseases.)