The Mouse as an Instrument for Ear Research II

描述（由申请人提供）：本申请为2005年10月1日至4日在缅因州巴尔港杰克逊实验室（TJL）举行的“鼠标作为耳朵研究仪器II”会议提供为期一年的支持。我们目前正处于一场遗传学革命之中，这场革命有望将“突破性”生物医学研究推向新的水平。这场革命的很大一部分取决于对基因之间关系及其对复杂生物系统和表型的影响的分析。研究人员必须越来越熟练地应用遗传模型来解决各种重要的生物学问题。本次会议的目的是为在视听神经生物学领域工作的研究人员和学生提供一个论坛。在过去，老鼠并不是研究听觉系统的主要实验动物。因此，“老鼠作为耳朵研究的工具II”被设计成一个论坛，在这个论坛上，研究非老鼠模型的研究人员和学生可以研究实验室老鼠的巨大潜力。此外，使用老鼠的研究人员将能够从该领域的其他专家那里扩展他们的技术知识。这个为期三天的会议包括几个教程和研讨会，旨在使参与者了解当代分析方法和使用实验室老鼠作为听觉研究的遗传工具。简短的演讲将详细介绍教程中展示的技术，并提供前沿研究的例子。大多数报告将是由组织者邀请的论文，但也有时间提供贡献论文和简短的摘要演讲。学生（博士预科和博士后）将不收取注册费，并将提供有限数量的旅行奖学金，以鼓励学生参与。最终，本次会议将汇集具有不同专业知识和经验的学生和知名研究人员，共同讨论他们的研究成果，确定共同研究兴趣的领域，并制定未来的方向。

DESCRIPTION (provided by applicant): This application is for one year of support for the meeting "The Mouse as an Instrument for Ear Research II" to be held at The Jackson Laboratory (TJL) in Bar Harbor, Maine on October 1-4, 2005. We are currently in the midst of a genetics revolution that promises to push "breakthrough" biomedical research to new levels. A large part of this revolution depends upon the analysis of the relationships between genes and their effects on complex biological systems and phenotypes. Investigators must become increasingly skilled in the application of genetic models to address a variety of important biological questions. The objective of this meeting is to provide a forum for researchers and students who work in areas of audio-sensory neurobiology. In the past the mouse has not been a major experimental animal for studying the auditory system. "The Mouse as an Instrument for Ear Research II" is therefore designed as a forum in which researchers and students studying non-murine models can investigate the enormous potential of the laboratory mouse. In addition, researchers using the mouse will be able to expand their knowledge of techniques from other experts in the field. This three-day meeting includes several tutorials and workshops designed to bring participants up to speed on Contemporary methods of analysis and the use of the laboratory mouse as a genetic tool for auditory research. Short presentations will elaborate on techniques demonstrated in the tutorials and provide examples of cutting edge research. Most presentations will be invited papers by the organizers but there are times available for contributed papers and short abstract talks. Students (pre and post doctoral) will not be charged a registration fee and a limited number of travel scholarships will be available to encourage student participation. Ultimately, this meeting will bring students and established investigators, with varying expertise and experience, together to discuss their research findings, identify areas of common research interest and develop future directions.