FIELD LIFE: Lifestyle Interactions in Fenofibrate and the Epigenome

遗传和环境因素影响糖尿病的血管(血管)、眼睛和肾脏并发症的风险，但这些因素相互作用的范围有多广还不太清楚。我们将检测血液中一类新的调节分子(称为microRNAs)的水平，以及DNA损伤的水平，并确定它们与血管风险因素以及心脏、脚、眼和肾脏损伤之间的联系，这些患者来自现场研究的2000名特征良好的澳大利亚2型糖尿病患者。

Genetic and environmental factors influence the risks of developing the blood vessel (vascular), eye and kidney complications of diabetes, but how extensively these factors interact is less well understood. We will examine blood levels of a new class of regulatory molecules (called microRNAs), and of DNA damage and identify how they are linked to vascular risk factors, and heart, foot, eye and kidney damage in 2000 well-characterised Australians with type 2 diabetes from the FIELD Study.