Developing SJCRH Animal Resources

描述（由申请人提供）： 本申请的目的是支持实验动物管理的合理计划。本申请建议购买设备，以改善圣裘德儿童研究医院（SJCRH）的动物护理设施和项目。我们计划的需求支持67名教师的知识产权，他们从公共卫生服务中直接获得约3400万美元的资金，用于医院的动物相关研究。为了实现这一目标并满足项目的需要，本提案的具体目标是购买维持转基因小鼠所需的通风架和笼子，并购买生物安全柜以进行笼子更换和小型实验程序。本申请中描述的设备将支持最高质量的动物护理，以保持无特定病原体的小鼠，并维持教师的研究工作。该设备还将提高我们动物设施的空间利用率，以确保其有效的长期使用。实现本申请的目的和具体目标将提高动物研究的质量，并促进治疗儿科癌症和其他儿童灾难性疾病所需的进展。

DESCRIPTION (provided by applicant): The objective of this application is to support a sound program of laboratory animal management. This application proposes to purchase equipment to make improvements in the animal care facilities and program at St. Jude Children's Research Hospital (SJCRH). The needs of our program support the intellectual property of 67 faculty who bring approximately $34 million in direct funds from the Public Health Service for animal related research to the hospital. To accomplish this objective and meet the needs of the program, the specific aims of this proposal are to purchase ventilated racks and cages needed for maintaining genetically altered mice and to purchase biological safety cabinets to perform cage changes and minor experimental procedures. The equipment described in this application will support the highest quality of animal care to maintain specific pathogen free mice, and to sustain the research efforts of the faculty. The equipment will also improve the utilization of space in our animal facility to ensure its efficient long-term use. Achieving the objective and specific aims of this application will improve the quality of animal research and promote the advances that are needed to treat pediatric cancer and other catastrophic diseases of children.