Neonatal Sucking Organization After Epidural Analgesia

描述（由申请人提供）：本两组比较研究的主要目的是研究分娩过程中胎儿暴露于母体硬膜外镇痛与出生后1小时初始喂养时新生儿神经行为组织（行为状态和吸吮组织）测量之间的关系。硬膜外镇痛对吸吮组织的相关影响以前没有被测量过。第二个目的是检查产妇和胎儿的急性应激反应（皮质醇）之间的关系在分娩过程中，新生儿的行为状态和吸吮组织。本研究的创新之处在于，胎儿在出生后快速适应的关键时期的应激反应减弱，是否是出生后吸吮组织初始发育的一个脆弱环节。这些发现将是在检查机制的第一步，和扰动，早期新生儿神经行为组织。新生儿神经行为组织发育的任何中断都有可能改变母婴互动和成功母乳喂养的建立，特别是在脆弱的双胎中。

DESCRIPTION (provided by applicant): The primary aim of this two group comparative study is to examine the relationship between fetal exposure to maternal epidural analgesia during labor and measures of neonatal neurobehavioral organization (behavioral state and sucking organization) in the initial feeding at one hour post birth. The associated effects of epidural analgesia on sucking organization have not been previously measured. The secondary aim is to examine the relationship between maternal and fetal acute stress responses (cortisol) during labor, and neonatal behavioral state and sucking organization. This research is innovative in exploring whether an attenuated fetal stress response during the critical period of rapid adaptation after birth is a vulnerable link in the initial development of sucking organization after birth. These findings will be an initial step in examining the mechanisms, and perturbations, of early neonatal neurobehavioral organization. Any disruption in the development of neonatal neurobehavioral organization has the potential to alter mother-infant interaction and the establishment of successful breastfeeding, especially in vulnerable dyads.